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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jan 15, 2025; 17(1): 99834
Published online Jan 15, 2025. doi: 10.4251/wjgo.v17.i1.99834
Published online Jan 15, 2025. doi: 10.4251/wjgo.v17.i1.99834
Advanced hepatocellular carcinoma treatment strategies: Are transarterial approaches leading the way?
Stefan Patauner, Giovanni Scotton, Francesca Notte, Antonio Frena, Department of General and Pediatric Surgery, Bolzano Central Hospital - SABES, Bolzano 39100, Trentino-Alto Adige, Italy
Co-first authors: Stefan Patauner and Giovanni Scotton.
Author contributions: Frena A designed the overall concept of the manuscript and revised the manuscript; Patauner S and Scotton G equally contributed to the design, review of the literature and writing of the manuscript; Notte F contributed to the review of the literature and editing of the manuscript; All authors contributed to this paper.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Antonio Frena, MD, PhD, Surgeon, Department of General and Pediatric Surgery, Bolzano Central Hospital - SABES, Via Boehler 5, Bolzano 39100, Trentino-Alto Adige, Italy. antonio.frena@sabes.it
Received: July 31, 2024
Revised: September 20, 2024
Accepted: September 25, 2024
Published online: January 15, 2025
Processing time: 133 Days and 22.1 Hours
Revised: September 20, 2024
Accepted: September 25, 2024
Published online: January 15, 2025
Processing time: 133 Days and 22.1 Hours
Core Tip
Core Tip: The treatment landscape for hepatocellular carcinoma (HCC) is various, including surgical resection, ablation, transplantation, transarterial, and systemic therapies. Each modality is selected based on tumor characteristics, liver function, and patient performance status. This editorial explores the role of hepatic arterial infusion chemotherapy and its combination strategies for advanced HCC, highlighting its potential advantages and advocating for its broader acceptance based on recent meta-analysis findings.