Observational Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Aug 15, 2024; 16(8): 3529-3538
Published online Aug 15, 2024. doi: 10.4251/wjgo.v16.i8.3529
Endoscopic detection and diagnostic strategies for minute gastric cancer: A real-world observational study
Xiao-Wei Ji, Jie Lin, Yan-Ting Wang, Jing-Jing Ruan, Jing-Hong Xu, Kai Song, Jian-Shan Mao
Xiao-Wei Ji, Jie Lin, Yan-Ting Wang, Jing-Jing Ruan, Jian-Shan Mao, Department of Gastroenterology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China
Jing-Hong Xu, Kai Song, Department of Pathology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China
Co-first authors: Xiao-Wei Ji and Jie Lin.
Author contributions: Ji XW and Lin J participated in data validation, analysis, and drafted the initial manuscript; Wang YT and Ruan JJ supervised the study and revised the manuscript; Xu JH and Song K performed pathological diagnosis; Mao JS was the guarantor who designed the study.
Supported by the National Science Foundation Committee of China, No 81372348; and Clinical Research Fund Project of Zhejiang Medical Association, No 2020ZYC-A10.
Institutional review board statement: The study was approved by the Research Ethics Committee of The Second Affiliated Hospital of Zhejiang University School of Medicine (Protocol No. 2022/0502).
Informed consent statement: Informed consent was waived after evaluation by the Research Ethics Committee.
Conflict-of-interest statement: The manuscript has been approved by all of the authors and there are no conflicts of interest.
Data sharing statement: The data presented in this study are available from the corresponding author upon reasonable request at jshmao@zju.edu.cn.
STROBE statement: The authors have read the STROBE Statement, and the manuscript was prepared and revised according to the STROBE Statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian-Shan Mao, MD, PhD, Chief, Department of Gastroenterology, The Second Affiliated Hospital, Zhejiang University School of Medicine, No. 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China. jshmao@zju.edu.cn
Received: April 24, 2024
Revised: May 26, 2024
Accepted: June 18, 2024
Published online: August 15, 2024
Processing time: 104 Days and 11.9 Hours
Core Tip

Core Tip: Minute gastric cancers (MGCs) represent the incipient stage of GC; therefore, they may be missed during endoscopy because the maximum diameter is ≤ 5 mm. Narrow-band imaging secondary observation combined with indigo carmine third observation could detect MGCs missed by white light endoscopy. A lesion with a clear demarcation line and a typical neoplastic color using nonmagnifying observation can be diagnosed as MGCs.