Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jun 15, 2024; 16(6): 2264-2270
Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2264
Dual primary gastric and colorectal cancer: The known hereditary causes and underlying mechanisms
Samy A Azer
Samy A Azer, Medical Education and Medicine, King Saud University College of Medicine, Riyadh 11461, Saudi Arabia
Author contributions: Azer SA has searched the literature, designed the editorial focus, wrote the early draft version of the manuscript, amended, edited and made changes, build the table needed, and approved the final version of the manuscript.
Conflict-of-interest statement: The author has no conflicts to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Samy A Azer, FACG, MD, PhD, Academic Editor, Medical Education and Medicine, King Saud University College of Medicine, P O Box 2925, Riyadh 11461, Saudi Arabia. azer2000@optusnet.com.au
Received: December 19, 2023
Revised: March 3, 2024
Accepted: April 7, 2024
Published online: June 15, 2024
Processing time: 178 Days and 14.5 Hours
Core Tip

Core Tip: Patients with dual primary synchronous and metachronous primary gastric and colorectal cancer should receive appropriate surveillance measures to minimize their risk of developing syndrome-specific cancers. The genetic testing of diffuse hereditary gastric cancer, familial adenomatous polyposis, hereditary nonpolyposis colon cancer, Lynch syndrome, Peutz-Jeghers syndrome, juvenile polyposis syndrome, and Cowden syndrome should be considered to ensure optimum diagnosis and management.