Retrospective Cohort Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. May 15, 2024; 16(5): 1773-1786
Published online May 15, 2024. doi: 10.4251/wjgo.v16.i5.1773
TRIANGLE operation, combined with adequate adjuvant chemotherapy, can improve the prognosis of pancreatic head cancer: A retrospective study
Jia-Hao Chen, Li-Yong Zhu, Zhi-Wei Cai, Xiao Hu, Abousalam Abdoulkader Ahmed, Jie-Qiong Ge, Xiao-Yan Tang, Chun-Jing Li, Yun-Long Pu, Chong-Yi Jiang
Jia-Hao Chen, Li-Yong Zhu, Zhi-Wei Cai, Xiao Hu, Abousalam Abdoulkader Ahmed, Xiao-Yan Tang, Chun-Jing Li, Yun-Long Pu, Chong-Yi Jiang, Department of Hepato-Biliary-Pancreatic Surgery, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China
Zhi-Wei Cai, Shanghai Key Laboratory of Clinical Geriatric Medicine, Fudan University, Shanghai 200040, China
Jie-Qiong Ge, Department of Nursing, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China
Co-first authors: Jia-Hao Chen and Li-Yong Zhu.
Author contributions: Chen JH, Jiang CY, Zhu LY, Cai ZW participated in the study design, data acquisition and interpretation, statistical analysis, drafting of the manuscript; Hu X, Ahmed AA, Ge JQ participated in the data acquisition and interpretation, statistical analysis, critical revision of the manuscript; Tang XY, Li CJ, Pu YL participated in the data acquisition and supervision, statistical analysis, critical revision of the manuscript; all authors had full access to all the data in the study and accept responsibility to submit for publication. Chen JH and Zhu LY contributed equally to this work as co-first authors. Together, Chen JH and Zhu LY paid the time and energy needed to complete the research and the final paper, assumed the related responsibilities and burdens, and completed the design, preparation, submission and other steps of this research. This also ensures that the quality and reliability of the paper is ultimately improved. Moreover, Chen JH and Zhu LY contributed efforts of equal substance throughout the research process, made the most significant intellectual contribution and contributed equally to this work. The choice of these researchers as co-authors acknowledges and respects this equal contribution, while recognizing the spirit of teamwork and collaboration of this study.
Supported by Shanghai Science and Technology Commission of Shanghai Municipality, No. 20Y11908600; Shanghai Municipal Health Commission, No. 20194Y0195; and Medical Engineering Jiont Fund of Fudan University, No. XM03231533.
Institutional review board statement: This study was conducted in accordance with the Declaration of Helsinki and received approval from the institutional review board of Huadong Hospital affiliated with Fudan University, and its protocol was declared and registered on ClinicalTrials.gov (ID: NCT05703581) before statistical analysis (January 30, 2023). This study was also approved by the Ethics Committee of Huadong Hospital Affiliated to Fudan University (No. 20170014), and all patients provided informed consent before the operation.
Informed consent statement: Informed consent was obtained from all individual participants.
Conflict-of-interest statement: The authors have no conficts of interest to declare.
Data sharing statement: The data supporting the findings of this study are available from the corresponding author upon reasonable request.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chong-Yi Jiang, MD, Chief Doctor, Department of Hepato-Biliary-Pancreatic Surgery, Huadong Hospital Affiliated to Fudan University, No. 221 Yan’an West Road, Shanghai 200040, China. jiangzhongyi9@sina.com
Received: January 7, 2024
Peer-review started: January 7, 2024
First decision: January 30, 2024
Revised: February 4, 2024
Accepted: March 5, 2024
Article in press: March 5, 2024
Published online: May 15, 2024
Processing time: 123 Days and 1.9 Hours
Core Tip

Core Tip: Although the TRIANGLE operation has shown efficacy in treating locally advanced pancreatic ductal adenocarcinoma (PDAC) patients, long-term oncological data from patients with resectable PDAC who underwent pancreaticoduodenectomy (PD) are limited. This study demonstrated the safety and efficacy of the TRIANGLE operation in reducing local recurrence of resectable PDAC and suggested survival benefits for patients receiving adequate adjuvant chemotherapy.