Zhu CL, Peng LZ. Clinical analysis of multiple primary gastrointestinal malignant tumors: A 10-year case review of a single-center. World J Gastrointest Oncol 2024; 16(4): 1204-1212 [PMID: 38660651 DOI: 10.4251/wjgo.v16.i4.1204]
Corresponding Author of This Article
Ling-Zhi Peng, MD, Chief Doctor, Department of Surgical Oncology, Gansu Provincial Hospital, No. 204 Donggang West Road, Chengguan District, Lanzhou 730000, Gansu Province, China. plz198996@163.com
Research Domain of This Article
Oncology
Article-Type of This Article
Retrospective Cohort Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Oncol. Apr 15, 2024; 16(4): 1204-1212 Published online Apr 15, 2024. doi: 10.4251/wjgo.v16.i4.1204
Clinical analysis of multiple primary gastrointestinal malignant tumors: A 10-year case review of a single-center
Cheng-Lou Zhu, Ling-Zhi Peng
Cheng-Lou Zhu, Ling-Zhi Peng, The First School of Clinical Medicine, Lanzhou University, Lanzhou 730000, Gansu Province, China
Cheng-Lou Zhu, Ling-Zhi Peng, Department of Surgical Oncology, Gansu Provincial Hospital, Lanzhou 730000, Gansu Province, China
Author contributions: Zhu CL and Peng LZ made significant contributions to the conceptualization and the design of this study; Zhu CL and Peng LZ collected all the data; Zhu CL and Peng LZ were the main contributors to this manuscript; Zhu CL and Peng LZ made significant revisions to this manuscript; All authors contributed to the article and approved the submitted version.
Supported bythe Natural Science Foundation of Gansu Province, No. 23JRRA1317, and No. 22JR11RA252.
Institutional review board statement: Our study was approved by The Medical Ethics Committee of Gansu Provincial Hospital, No. 2022-191.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: All data generated or analysed during this study are included in this article. Further enquiries can be directed to the corresponding author at plz198996@163.com.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ling-Zhi Peng, MD, Chief Doctor, Department of Surgical Oncology, Gansu Provincial Hospital, No. 204 Donggang West Road, Chengguan District, Lanzhou 730000, Gansu Province, China. plz198996@163.com
Received: January 13, 2024 Peer-review started: January 13, 2024 First decision: January 30, 2024 Revised: February 2, 2024 Accepted: March 6, 2024 Article in press: March 6, 2024 Published online: April 15, 2024 Processing time: 88 Days and 10.1 Hours
Core Tip
Core Tip: Despite improvement in understanding of multiple primary malignant tumors (MPMTs), their pathogenesis remains unclear. Herein, we analyzed the incidence of MPMTs in the gastrointestinal tract, the different tumor combinations, time intervals between the occurrence of tumors, staging, clinical course, and prognostic features. Our aim was to determine whether the gastrointestinal tract is particularly susceptible to second or third primary cancers, and to promote early diagnosis. Our results suggested that MPMTs in the gastrointestinal tract have a high incidence and poor prognosis, and both gastroscopy and colonoscopy are necessary in patients with gastrointestinal tumors. Multidisciplinary comprehensive diagnosis and treatment may improve MPMT diagnosis and treatment.
