Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Mar 15, 2024; 16(3): 1076-1083
Published online Mar 15, 2024. doi: 10.4251/wjgo.v16.i3.1076
Managing end-stage carcinoid heart disease: A case report and literature review
Nikola Bulj, Vedran Tomasic, Maja Cigrovski Berkovic
Nikola Bulj, Department of Cardiology, University Hospital Centre “Sestre Milosrdnice,“ Zagreb 10000, Croatia
Vedran Tomasic, Division of Gastroenterology, Department of Internal Medicine, University Hospital Centre “Sestre Milosrdnice,” Zagreb 10000, Croatia
Maja Cigrovski Berkovic, Department for Sport and Exercise Medicine, University of Zagreb Faculty of Kinesiology, Zagreb 10000, Croatia
Author contributions: Bulj N collected data and drafted the manuscript; Tomasic V collected data, drafted, and wrote the manuscript; Cigrovski Berkovic M contributed to the conception and design of the study, drafted, and revised the manuscript critically; All authors read and approved the final manuscript.
Informed consent statement: We present a case of a deceased patient born in 1975 (who died in 2014) reconstructed from available medical records and electronic data and discuss it considering the current diagnostic and treatment options. Due to the mentioned informed consent could not be obtained. This was a retrospective analysis of the electronic records, and the informed consent was waived.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
CARE Checklist (2016) statement: The authors have read CARE Checklist (2016), and the manuscript was prepared and revised according to CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed by the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Maja Cigrovski Berkovic, MD, Adjunct Associate Professor, Department for Sport and Exercise Medicine, University of Zagreb Faculty of Kinesiology, Horvacanski zavoj 15, Zagreb 10000, Croatia. maja.cigrovskiberkovic@gmail.com
Received: October 13, 2023
Peer-review started: October 13, 2023
First decision: December 15, 2023
Revised: December 26, 2023
Accepted: January 24, 2024
Article in press: January 24, 2024
Published online: March 15, 2024
Processing time: 150 Days and 22.2 Hours
Core Tip

Core Tip: Cardiovascular complications of neuroendocrine neoplasms are the leading cause of death, even compared to metastatic disease. Early detection of right ventricular dysfunction and changes in the tricuspid valve are crucial. Here, we present a patient with advanced carcinoid heart disease with a poor prognosis. Considering current recommendations, it seems reasonable to search for subclinical right-sided heart damage by determining N-terminal pro b-type natriuretic peptide in patients with elevated biomarker values and neuroendocrine tumors, resulting in earlier diagnosis and treatment.