Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Dec 15, 2024; 16(12): 4650-4662
Published online Dec 15, 2024. doi: 10.4251/wjgo.v16.i12.4650
Nomogram model based on γ-glutamyl transferase to albumin ratio predicts survival in hepatocellular carcinoma patients with transarterial chemoembolization treatment
Zhen-Ying Wu, Han Li, Jia-Li Chen, Ke Su, Mei-Ling Weng, Yun-Wei Han
Zhen-Ying Wu, Han Li, Jia-Li Chen, Mei-Ling Weng, Yun-Wei Han, Department of Oncology, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China
Zhen-Ying Wu, Department of Oncology, Pangang Group General Hospital, Panzhihua 617000, Sichuan Province, China
Ke Su, Department of Oncology, National Cancer Center, Beijing 100000, China
Ke Su, Department of Oncology, National Clinical Research Center for Cancer, Beijing 100000, China
Ke Su, Department of Oncology, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100000, China
Co-first authors: Zhen-Ying Wu and Han Li.
Author contributions: Wu ZY, Li H, and Han YW conceived, designed and refined the study protocol; Chen JL, Su K, and Weng ML were involved in the data collection and formulation of research objectives; Wu ZY and Li H drafted the manuscript; and all authors were involved in the critical review of the results and approved the final manuscript. Wu ZY and Li H contributed equally to this work. The reasons for designating Wu ZY and Li H as co-first authors are threefold. First, the research was performed as a collaborative effort, and the designation of co-first authorship accurately reflects the distribution of responsibilities and burdens associated with the time and effort required to complete the study and the resultant paper. This also ensures effective communication and management of post-submission matters, ultimately enhancing the paper’s quality and reliability. Second, the overall research team encompassed authors with a variety of expertise and skills from different fields, and the designation of co-first authors best reflect this diversity. This also promotes the most comprehensive and in-depth examination of the research topic, ultimately enriching readers’ understanding by offering various expert perspectives. Third, Wu ZY and Li H contributed efforts of equal substance throughout the research process. They equally made a significant contribution to the work reported, in the design of methodology, creation of models, testing of code, statistical analysis, validation of results, writing the initial draft, and revision of articles. The choice of these researchers as co-first authors acknowledge and respects this equal contribution, while recognizing the spirit of teamwork and collaboration of this study. In summary, we believe that designating Wu ZY and Li H as co-first authors of are fitting for our manuscript as it accurately reflects our team’s collaborative spirit, equal contributions, and diversity.
Institutional review board statement: The study protocol was authorized by the Ethics Committee of the Affiliated Hospital of Southwest Medical University (No. KY2021063) and complied with the Code of Ethics of the World Medical Association.
Informed consent statement: Written informed consent was waived because of the retrospective study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: All data generated or analyzed during this study are included in this article and its Supplementary material files. Further inquiries can be directed to the corresponding author (lanpaoxiansheng@126.com).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yun-Wei Han, MD, PhD, Academic Research, Full Professor, Department of Oncology, The Affiliated Hospital of Southwest Medical University, No. 25 Taiping Street, Jiangyang District, Luzhou 646000, Sichuan Province, China. lanpaoxiansheng@126.com
Received: June 13, 2024
Revised: September 16, 2024
Accepted: October 11, 2024
Published online: December 15, 2024
Processing time: 152 Days and 4.4 Hours
Core Tip

Core Tip: γ-glutamyl transferase to albumin ratio has been confirmed for the first time to be predictive in hepatocellular carcinoma undergoing transarterial chemoembolization and transarterial chemoembolization combined with systemic therapy in this large-sample multicenter study. A nomogram model for predicting postoperative survival was also established based on γ-glutamyl transferase to albumin ratio, which was empirically demonstrated to have strong predictive ability.