Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Oct 15, 2024; 16(10): 4138-4145
Published online Oct 15, 2024. doi: 10.4251/wjgo.v16.i10.4138
Clinicopathological analysis of small intestinal metastasis from extra-abdominal/extra-pelvic malignancy
Zhi Zhang, Jing Liu, Peng-Fei Yu, Hai-Rui Yang, Jin-Yang Li, Zhi-Wei Dong, Wei Shi, Guo-Li Gu
Zhi Zhang, Department of General Surgery, Anhui Medical University First Affiliated Hospital, Hefei 230002, Anhui Province, China
Jing Liu, Department of General Surgery, Air Force Clinical College, China Medical University, Beijing 100142, China
Peng-Fei Yu, Zhi-Wei Dong, Guo-Li Gu, Department of General Surgery, Air Force Medical Center, Air Force Clinical College of China Medical University, Beijing 100142, China
Hai-Rui Yang, Department of General Surgery, Air Force Medical Center, Chinese People’s Liberation Army, Fifth Clinical (Air Force Clinical College) of China Medical University, Beijing 100142, China
Jin-Yang Li, Department of General Surgery, Beijing Changping Hospital, Beijing 102200, China
Wei Shi, Department of General Surgery, Air Force Medical Center, Beijing 100142, China
Co-first authors: Zhi Zhang and Jing Liu.
Co-corresponding authors: Wei Shi and Guo-Li Gu.
Author contributions: Zhang Z and Liu J contributed equally to this study, they are the co-first authors of this manuscript. Shi W and Gu GL designed the research; Zhang Z and Liu J conceived of the study, developed the methodology, collected data, analyzed and interpreted data, and written the manuscript; Yu PF, Yang HR, Li JY, and Dong ZW managed the patients, collected and analyzed the clinical data; Shi W and Gu GL provided the material support, revised the manuscript, they are the co-corresponding authors of this manuscript. All authors approved the final manuscript.
Supported by Outstanding Young Talents Program of Air Force Medical Center, People’s Liberation Army, No. 22BJQN004; and Clinical Program of Air Force Medical University, No. Xiaoke2022-07.
Institutional review board statement: The Air Force Medical Center Ethics Committee reviewed and approved the study, approval No. 2024-105-PJ01.
Informed consent statement: The patients were informed of the purpose of the study, and signed an informed consent form.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Guo-Li Gu, Doctor, MD, Chief Doctor, Department of General Surgery, Air Force Medical Center, Air Force Clinical College of China Medical University, No. 30 Fucheng Road, Haidian District, Beijing 100142, China. kzggl@163.com
Received: July 18, 2024
Revised: August 18, 2024
Accepted: August 26, 2024
Published online: October 15, 2024
Processing time: 70 Days and 1.9 Hours
Core Tip

Core Tip: The metastatic tumors in the small intestine secondary to extra-abdominal/extra-pelvic malignancy are extremely rare. This study intends to identify the clinicopathological characteristics of small intestinal metastases from extra-abdominal/extra-pelvic malignancy. Eleven patients with small intestinal metastases from extra-abdominal/extra-pelvic malignancy diagnosed and treated in the Air Force Medical Center from 2005 to 2024 were enrolled. The results showed that small intestinal metastases from extra-abdominal/extra-pelvic malignancy is rare in clinic, with high malignancy and great difficulty in diagnosis and treatment. Clinically, patients with extra-abdominal/extra-pelvic malignancy should be alert to the occurrence of this disease, and their prognosis may be improved through active surgery combined with standard targeted therapy.