Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Aug 15, 2023; 15(8): 1475-1485
Published online Aug 15, 2023. doi: 10.4251/wjgo.v15.i8.1475
Carcinoembryonic antigen, carbohydrate antigen 199 and carbohydrate antigen 724 in gastric cancer and their relationship with clinical prognosis
Ran Wang, Chun-Lei Zuo, Rui Zhang, Li-Mei Zhu
Ran Wang, Chun-Lei Zuo, Rui Zhang, Li-Mei Zhu, Department of Medical Laboratory, The First People’s Hospital of Lianyungang, Lianyungang 222002, Jiangsu Province, China
Author contributions: Zhu LM designed the study; Wang R and Zhu LM wrote the manuscript; Wang R and Zuo CL performed the experiments; Wang R and Zhang R analysed the data; and all authors have read and approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by Ethics Committee of The First People’s Hospital of Lianyungang.
Informed consent statement: All patient data obtained, recorded, and managed only used for this study, and all patient information are strictly confidential, without any harm to the patient, so the informed consent was waived by the Ethics Committee of The First People’s Hospital of Lianyungang.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Li-Mei Zhu, MM, Chief Doctor, Department of Medical Laboratory, The First People’s Hospital of Lianyungang, No. 182 Tongguan North Road, Lianyungang 222002, Jiangsu Province, China. zlm5902@163.com
Received: June 20, 2023
Peer-review started: June 20, 2023
First decision: July 7, 2023
Revised: July 17, 2023
Accepted: July 27, 2023
Article in press: July 27, 2023
Published online: August 15, 2023
Processing time: 51 Days and 6.7 Hours
Core Tip

Core Tip: In this retrospective analysis, the expression levels of tumor markers carcinoembryonic antigen (CEA), carbohydrate antigen 199 (CA199) and carbohydrate antigen 724 (CA724) in gastric cancer (GC) patients and normal people were detected. In addition, the serum CEA, CA199 and CA724 levels in GC patients with different TNM stages, and the differences in the positive rates of TNM stages of GC and GC detected by CEA, CA199 and CA724 alone and in combination were compared. The relationship between tumor markers CEA, CA199 and CA724 levels and clinicopathological characteristics of GC patients was analyzed.