Xie CB, Wu Y, Li F, Zhao KF, Shi RS, Huang Q, Ao J, Ke D. Primary signet-ring cell carcinoma of the extrahepatic bile duct: A case report. World J Gastrointest Oncol 2022; 14(7): 1356-1362 [PMID: 36051105 DOI: 10.4251/wjgo.v14.i7.1356]
Corresponding Author of This Article
Kai-Fei Zhao, Doctor, Associate Professor, Deputy Director, Department of Radiology, The Affiliated Hospital of Zunyi Medical University, No. 149 Dalian Road, Zunyi 563000, Guizhou Province, China. zhaokaifei8943@sina.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Oncol. Jul 15, 2022; 14(7): 1356-1362 Published online Jul 15, 2022. doi: 10.4251/wjgo.v14.i7.1356
Primary signet-ring cell carcinoma of the extrahepatic bile duct: A case report
Chao-Bang Xie, Yang Wu, Feng Li, Kai-Fei Zhao, Rong-Shu Shi, Qiong Huang, Jin Ao, Di Ke
Chao-Bang Xie, Yang Wu, Feng Li, Kai-Fei Zhao, Rong-Shu Shi, Jin Ao, Di Ke, Department of Radiology, The Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou Province, China
Qiong Huang, Department of Pathology, The Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou Province, China
Author contributions: Xie CB, Wu Y, Li F, and Zhao KF reviewed the literature and contributed to manuscript drafting; Shi RS analyzed and interpreted the patient data; Huang Q provided pathological images; Ao J and Ke D managed the patient; all authors read and approved the final manuscript.
Supported bythe Zunyi City Science and Technology Department, No. HZ-2021-44.
Informed consent statement: Informed consent was obtained from the patient’ family for the publication of this case as the patient has deceased.
Conflict-of-interest statement: We have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kai-Fei Zhao, Doctor, Associate Professor, Deputy Director, Department of Radiology, The Affiliated Hospital of Zunyi Medical University, No. 149 Dalian Road, Zunyi 563000, Guizhou Province, China. zhaokaifei8943@sina.com
Received: January 23, 2022 Peer-review started: January 23, 2022 First decision: April 17, 2022 Revised: April 30, 2022 Accepted: June 21, 2022 Article in press: June 21, 2022 Published online: July 15, 2022 Processing time: 170 Days and 15.8 Hours
Core Tip
Core Tip: We report a case where an 82-year-old female was admitted with abdominal pain, jaundice, and skin pruritus for 2 mo. The radiological diagnosis was a cholangiocarcinoma. To alleviate jaundice and prolong the overall survival, percutaneous transhepatic cholangiopancreatic drainage (PTCD) was performed. During the operation, in order to determine the nature and origin of the lesion, a biliary biopsy was performed under fluoroscopy. Finally, a diagnosis of primary signet ring cell carcinoma of extrahepatic bile duct with distant lymph node metastasis and multiple liver metastases was made based on the radiographic, PTCD, and pathological characteristics. However, despite active treatment, the disease progressed rapidly, and the patient died after 1 mo due to liver failure.
