Retrospective Cohort Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jun 15, 2022; 14(6): 1148-1161
Published online Jun 15, 2022. doi: 10.4251/wjgo.v14.i6.1148
Contemporary, national patterns of surgery after preoperative therapy for stage II/III rectal adenocarcinoma
Celine Soriano, Henry T Bahnson, Jennifer A Kaplan, Bruce Lin, Ravi Moonka, Huong T Pham, Hagen F Kennecke, Vlad Simianu
Celine Soriano, Jennifer A Kaplan, Ravi Moonka, Department of Surgery, Virginia Mason Franciscan Health, Seattle, WA 98101, United States
Henry T Bahnson, Benaroya Research Institute, Seattle, WA 98101, United States
Bruce Lin, Department of Hematology Oncology, Virginia Mason Franciscan Health, Seattle, WA 98101, United States
Huong T Pham, Department of Radiation Oncology, Virginia Mason Franciscan Health, Seattle, WA 98101, United States
Hagen F Kennecke, Department of Medical Oncology, Providence Cancer Instititute, Portland, OR 97213, United States
Vlad Simianu, Section of Colon and Rectal Surgery, Department of Surgery, Virginia Mason Medical Center, Seattle, WA 98101, United States
Author contributions: All authors have made substantial contributions to conception and design of the study, acquisition of data, or analysis and interpretation of data, been actively involved in drafting the article or making critical revisions related to important intellectual content of the manuscript, and have provided final approval of the version of the article to be published.
Institutional review board statement: The study was reviewed and approved for publication by our Institutional Reviewer.
Conflict-of-interest statement: All the Authors have no conflict of interest related to the manuscript.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE statement, and the manuscript was prepared and revised according to the STROBE statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Vlad Simianu, FACS, MD, Director, Surgeon, Section of Colon and Rectal Surgery, Department of Surgery, Virginia Mason Medical Center, 1100 Ninth Ave C6-GS, Seattle, WA 98101, United States. vlad.simianu@commonspirit.org
Received: December 29, 2021
Peer-review started: December 29, 2021
First decision: March 13, 2022
Revised: April 11, 2022
Accepted: May 22, 2022
Article in press: May 22, 2022
Published online: June 15, 2022
Processing time: 162 Days and 21.6 Hours
Core Tip

Core Tip: At a population level, there have been increases in neoadjuvant treatment and minimally-invasive surgical (MIS) approaches for stage II and III rectal cancer. These shifts have are not associated with changes in rates of permanent ostomy which remain about 30%. In contrast to prior trials, this ‘real-world’ cohort showed an association with higher quality surgical resection and improved survival with MIS.