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World J Gastrointest Oncol. Feb 15, 2022; 14(2): 413-422
Published online Feb 15, 2022. doi: 10.4251/wjgo.v14.i2.413
Small bowel adenocarcinoma: An overview
Divya Khosla, Treshita Dey, Renu Madan, Rahul Gupta, Shikha Goyal, Narendra Kumar, Rakesh Kapoor
Divya Khosla, Treshita Dey, Renu Madan, Shikha Goyal, Narendra Kumar, Rakesh Kapoor, Department of Radiotherapy and Oncology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
Rahul Gupta, Department of Gastroenterology, Shalby Multispeciality Hospital, Mohali 160062, Punjab, India
Author contributions: Khosla D contributed to conceptualization, manuscript preparation, writing and editing, and was responsible for the integrity of article; Dey T contributed to the literature search and manuscript writing and editing; Madan R contributed to the literature search; Gupta R contributed to the literature search and manuscript writing and editing; Goyal S contributed to editing; Kumar N and Kapoor R reviewed and approved the manuscript.
Conflict-of-interest statement: The author declares no conflicts of interest in the preparation of the manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Divya Khosla, MD, Assistant Professor, Department of Radiotherapy and Oncology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India. dr_divya_khosla@yahoo.com
Received: March 11, 2021
Peer-review started: March 11, 2021
First decision: July 16, 2021
Revised: August 9, 2021
Accepted: January 22, 2022
Article in press: January 22, 2022
Published online: February 15, 2022
Processing time: 336 Days and 0.9 Hours
Core Tip

Core Tip: Small bowel adenocarcinoma are rare malignancies with a poor prognosis. These are often diagnosed in the advanced stage owing to the non-specific nature of symptoms. The clinical presentation is varied and vague, and a high index of suspicion is required for prompt diagnosis and treatment. The most common site of presentation is the duodenum. Surgical resection with negative margins and adequate lymph node dissection remains the mainstay of treatment. Since the disease is rare, there is a paucity of prospective data. The treatment is generally extrapolated from the evidence available from colonic cancers. We have discussed all the aspects of this small bowel cancer comprehensively.