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World J Gastrointest Oncol. Jan 15, 2022; 14(1): 230-241
Published online Jan 15, 2022. doi: 10.4251/wjgo.v14.i1.230
Early-onset colorectal cancer: Current insights and future directions
Claudia Wing-Kwan Wu, Rashid N Lui
Claudia Wing-Kwan Wu, Rashid N Lui, Division of Gastroenterology and Hepatology, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China
Rashid N Lui, Department of Clinical Oncology, The Chinese University of Hong Kong, Hong Kong, China
Author contributions: Wu CWK and Lui RN contributed equally to this work; all authors have read and approved the final manuscript.
Conflict-of-interest statement: All authors have no conflicts of interest to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Rashid N Lui, MBChB, FRCP, Clinical Assistant Professor (Honorary), Division of Gastroenterology and Hepatology, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China. rashidlui@cuhk.edu.hk
Received: June 16, 2021
Peer-review started: June 16, 2021
First decision: July 29, 2021
Revised: August 2, 2021
Accepted: November 24, 2021
Article in press: November 24, 2021
Published online: January 15, 2022
Processing time: 208 Days and 8.8 Hours
Core Tip

Core Tip: The incidence of early onset colorectal cancer is on the rise. Herein, we discuss on various risk factors that have been implicated for these recent trends and point to where future research needs to be directed for better utilization of healthcare resources. Early recognition and diagnosis are essential for better outcomes of this preventable cancer.