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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Dec 15, 2021; 13(12): 2013-2028
Published online Dec 15, 2021. doi: 10.4251/wjgo.v13.i12.2013
Published online Dec 15, 2021. doi: 10.4251/wjgo.v13.i12.2013
Macrophages play a role in inflammatory transformation of colorectal cancer
Lu Lu, Yu-Jing Liu, Pei-Qiu Cheng, Han-Chen Xu, Guang Ji, Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
Dan Hu, Han-Chen Xu, Shanghai Pudong New Area Hospital of Traditional Chinese Medicine, Shanghai 200120, China
Author contributions: Lu L, Liu YJ, Cheng PQ, and Hu D wrote the manuscript; Ji G and Xu HC are co-corresponding authors, and they contributed to editing the manuscript; all authors wrote, read, and approved the final manuscript.
Supported by The National Nature Science Foundation of China , No. 81874206 ; Shanghai Rising-Star Program , No. 20QA1409300 ; and the Program for Young Eastern Scholar at Shanghai Institutions of Higher Learning , No. QD2019034 .
Conflict-of-interest statement: There is no conflict of interest associated with any of the senior author or other coauthors who contributed their efforts in this manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Guang Ji, MD, PhD, Chief Doctor, Professor, Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, No. 725 South Wanping Road, Shanghai 200032, China. jiliver@vip.sina.com
Received: May 17, 2021
Peer-review started: May 17, 2021
First decision: July 14, 2021
Revised: July 21, 2021
Accepted: August 25, 2021
Article in press: August 25, 2021
Published online: December 15, 2021
Peer-review started: May 17, 2021
First decision: July 14, 2021
Revised: July 21, 2021
Accepted: August 25, 2021
Article in press: August 25, 2021
Published online: December 15, 2021
Core Tip
Core Tip: In this review, we provide a comprehensive review of the research progress of macrophages in intestinal inflammation and colorectal cancer. It is of great signi