Systematic Reviews
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Feb 15, 2020; 12(2): 228-236
Published online Feb 15, 2020. doi: 10.4251/wjgo.v12.i2.228
Yttrium-90 radioembolization for unresectable hepatic metastases of breast cancer: A systematic review
Michael Feretis, Andriy Solodkyy
Michael Feretis, Department of Surgery, Addenbrooke’s Hospital, Cambridge CB2 0QQ, United Kingdom
Andriy Solodkyy, Department of General Surgery, Hinchingbrooke Hospital, North West Anglia NHS Foundation Trust, Huntingdon PE29 6NT, United Kingdom
Author contributions: Feretis M and Solodkyy A wrote the paper, Feretis M and Solodky A read and approved the final manuscript.
Conflict-of-interest statement: All the authors declare that they have no competing interests.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Michael Feretis, MBChB, Surgical Oncologist, Department of Surgery, Level 9, Addenbrooke’s Hospital, Cambridge University Hospitals, NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, United Kingdom. micferetis83@gmail.com
Received: October 8, 2019
Peer-review started: October 8, 2019
First decision: November 11, 2019
Revised: December 19, 2019
Accepted: January 6, 2020
Article in press: January 6, 2020
Published online: February 15, 2020
Processing time: 130 Days and 0.6 Hours
Core Tip

Core tip: This is the first systematic review on the subject of liver radioembolization with yttrium-90 for breast metastases. Our paper reports cumulative findings of the 12 studies included on two important outcomes that of tumour response to embolization and patient survival. The paper summarises the current evidence available in the field and also makes recommendations for future areas of research in clinical practice.