Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jan 15, 2020; 12(1): 1-20
Published online Jan 15, 2020. doi: 10.4251/wjgo.v12.i1.1
Precision medicine for gastrointestinal cancer: Recent progress and future perspective
Tasuku Matsuoka, Masakazu Yashiro
Tasuku Matsuoka, Masakazu Yashiro, Department of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Osaka 5458585, Japan
Masakazu Yashiro, Oncology Institute of Geriatrics and Medical Science, Osaka City University Graduate School of Medicine, Osaka 5458585, Japan
Author contributions: Matsuoka T and Yahiro M performed literature research; Matsuoka T wrote the manuscript and performed the revision and approval of the final version; Yahiro M designed research, coordinated and corrected the writing of the paper.
Supported by KAKENHI (Grant-in-Aid for Scientific Research), No. 18H02883.
Conflict-of-interest statement: There are not any financial or other interests regarding the submitted manuscript that might be construed as a conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Masakazu Yashiro, MD, PhD, Associate Professor, Department of Surgical Oncology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka 5458585, Japan.
Received: March 14, 2019
Peer-review started: March 15, 2019
First decision: July 31, 2019
Revised: October 12, 2019
Accepted: November 4, 2019
Article in press: November 4, 2019
Published online: January 15, 2020
Core Tip

Core tip: Gastrointestinal (GI) cancer is one of the most common leading causes of cancer death worldwide. Hence, any effort in early diagnosis, choice of appropriate therapeutic strategies can have a pivotal role in reducing the disease related mortalities. Our review purpose to clarify the current advancement for precision medicine in GI cancer by elucidating the benefit of liquid biopsy, multiple gene panel, novel biomarkers and surgery in GI cancer.