De Raffele E, Mirarchi M, Cuicchi D, Lecce F, Ricci C, Casadei R, Cola B, Minni F. Simultaneous curative resection of double colorectal carcinoma with synchronous bilobar liver metastases. World J Gastrointest Oncol 2018; 10(10): 293-316 [PMID: 30364774 DOI: 10.4251/wjgo.v10.i10.293]
Corresponding Author of This Article
Emilio De Raffele, MD, PhD, Surgeon, Surgical Oncologist, Unità Operativa di Chirurgia Generale, Dipartimento dell’Apparato Digerente, Azienda Ospedaliero-Universitaria di Bologna, Policlinico S.Orsola-Malpighi, Via Massarenti 9, Bologna 40138, Italy. e.deraffele@aosp.bo.it
Research Domain of This Article
Oncology
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Oncol. Oct 15, 2018; 10(10): 293-316 Published online Oct 15, 2018. doi: 10.4251/wjgo.v10.i10.293
Simultaneous curative resection of double colorectal carcinoma with synchronous bilobar liver metastases
Emilio De Raffele, Mariateresa Mirarchi, Dajana Cuicchi, Ferdinando Lecce, Claudio Ricci, Riccardo Casadei, Bruno Cola, Francesco Minni
Emilio De Raffele, Dajana Cuicchi, Ferdinando Lecce, Claudio Ricci, Riccardo Casadei, Francesco Minni, Unità Operativa di Chirurgia Generale, Dipartimento dell’Apparato Digerente, Azienda Ospedaliero-Universitaria di Bologna, Policlinico S.Orsola-Malpighi, Bologna 40138, Italy
Mariateresa Mirarchi, U.O. di Chirurgia Generale, Dipartimento Strutturale Chirurgico, Ospedale “Antonio e Margherita, ” Tortona (AL) 15057, Italy
Bruno Cola, Dipartimento di Scienze Mediche e Chirurgiche (DIMEC), Alma Mater Studiorum, Policlinico S.Orsola-Malpighi, University of Bologna, Bologna 40138, Italy
Author contributions: De Raffele E and Mirarchi M contributed to the conception and design of the study, acquisition, analysis, and interpretation of data, and wrote the manuscript; Cuicchi D, Lecce F, Ricci C and Casadei R contributed to acquisition, analysis, and interpretation of data; Cola B and Minni F made critical revisions and final approval of the paper.
Conflict-of-interest statement: The authors have no conflict of interest related to this publication.
Open-Access: This article is an open-access article, which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Emilio De Raffele, MD, PhD, Surgeon, Surgical Oncologist, Unità Operativa di Chirurgia Generale, Dipartimento dell’Apparato Digerente, Azienda Ospedaliero-Universitaria di Bologna, Policlinico S.Orsola-Malpighi, Via Massarenti 9, Bologna 40138, Italy. e.deraffele@aosp.bo.it
Telephone: +39-51-6364235
Received: June 9, 2018 Peer-review started: June 9, 2018 First decision: July 13, 2018 Revised: July 28, 2018 Accepted: August 21, 2018 Article in press: August 21, 2018 Published online: October 15, 2018 Processing time: 128 Days and 21.9 Hours
Core Tip
Core tip: Simultaneous colorectal and liver resection represents an appealing surgical strategy in selected patients with colorectal cancer and resectable synchronous liver metastases (CRLM). Synchronous colorectal carcinoma may represent an adequate indication to simultaneous resections, even though it may require more complex colorectal resections. In patients with multiple bilobar synchronous CRLM, major hepatectomies performed simultaneously with colorectal surgery have been associated with increased perioperative risks compared to major hepatectomies alone. Conservative or parenchymal-sparing hepatectomies reduce the extent of hepatectomy while preserving oncological radicality, and may represent the best option to reduce the perioperative risks of simultaneous colorectal and liver resection.
