Tang JC, Ma JW, Jian JJ, Shen J, Cao LL. Effect of different anesthetic modalities with multimodal analgesia on postoperative pain level in colorectal tumor patients. World J Gastrointest Oncol 2024; 16(2): 364-371 [PMID: 38425386 DOI: 10.4251/wjgo.v16.i2.364]
Corresponding Author of This Article
Jia-Wei Ma, MD, Doctor, Department of Critical Care Medicine, Central Hospital Affiliated to Jiangnan University, No. 1800 Lihu Avenue, Wuxi 214122, Jiangsu Province, China. mjw081x@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Oncol. Feb 15, 2024; 16(2): 364-371 Published online Feb 15, 2024. doi: 10.4251/wjgo.v16.i2.364
Effect of different anesthetic modalities with multimodal analgesia on postoperative pain level in colorectal tumor patients
Ji-Chun Tang, Jia-Wei Ma, Jin-Jin Jian, Jie Shen, Liang-Liang Cao
Ji-Chun Tang, Jin-Jin Jian, Liang-Liang Cao, Department of Anesthesiology, The Affiliated Hospital of Jiangnan University, Wuxi 214122, Jiangsu Province, China
Ji-Chun Tang, Department of Anesthesiology, People's Hospital of Aheqi County, Kizilsu Kirgiz Autonomous Prefecture 843599, Xinjiang Uygur Autonomous Region, China
Jia-Wei Ma, Department of Critical Care Medicine, Jiangnan University Medical Center, Wuxi 214122, Jiangsu Province, China
Jia-Wei Ma, Department of Critical Care Medicine, People's Hospital of Aheqi County, Kizilsu Kirgiz Autonomous Prefecture, 843599, Xinjiang Uygur Autonomous Region, China
Jie Shen, Department of Anesthesiology, Jiangyuan Hospital Affiliated to Jiangsu Institute of Atomic Medicine, Wuxi 214063, Jiangsu Province, China
Author contributions: Wang CL and Liang L contributed equally to this work; Wang CL, Liang L, Fu JF, Zou CC, Hong F and Wu XM designed the research study; Wang CL, Zou CC, Hong F and Wu XM performed the research; Xue JZ and Lu JR contributed new reagents and analytic tools; Wang CL, Liang L and Fu JF analyzed the data and wrote the manuscript; all authors have read and approve the final manuscript.
Institutional review board statement: The Institutional Review Board at our hospital approved the study (Approval No. 32432891).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jia-Wei Ma, MD, Doctor, Department of Critical Care Medicine, Central Hospital Affiliated to Jiangnan University, No. 1800 Lihu Avenue, Wuxi 214122, Jiangsu Province, China. mjw081x@163.com
Received: September 7, 2023 Peer-review started: September 7, 2023 First decision: September 26, 2023 Revised: November 11, 2023 Accepted: December 25, 2023 Article in press: December 25, 2023 Published online: February 15, 2024 Processing time: 148 Days and 6.3 Hours
ARTICLE HIGHLIGHTS
Research background
Postoperative pain management is crucial in patient care, as a significant number of patients experience pain after surgery. The current approach involves intravenous self-control analgesia using opioid analgesics. Surgery for colorectal cancer typically involves general anesthesia, and optimizing anesthesia management and postoperative analgesic programs can reduce stress and enhance recovery.
Research motivation
The study aims to assess the impact of different anesthesia modalities with multimodal analgesia on postoperative pain in patients with colorectal cancer. Understanding the effects of these combinations can help improve pain management strategies and patient outcomes.
Research objectives
The objective is to explore the effects of different anesthesia methods coupled with multi-mode analgesia on postoperative pain in patients with colorectal cancer.
Research methods
A total of 126 patients with colorectal cancer were included, with 63 in the control group receiving general anesthesia coupled with multi-mode labor pain, and 63 in the research group receiving general anesthesia associated with epidural anesthesia coupled with multi-mode labor pain. Data on postoperative analgesia, sedation, and recovery were collected and compared between the two groups.
Research results
The research group had significantly shorter recovery times for orientation, extubation, eye-opening, and spontaneous respiration compared to the control group. They also reported lower pain intensity scores and reduced opioid consumption within the first 24 h after surgery. However, the research group experienced a higher incidence of hypotension, nausea, and urinary retention. No significant differences were observed in sedation scores or postoperative complications between the two groups. In summary, combing epidural anesthesia with multi-mode analgesia may lead to superior postoperative pain management and faster recovery in patients with colorectal cancer. However, it may also increase the risk of certain side effects. These findings highlight the importance of individualized pain management strategies and careful consideration of patient characteristics and medical history when selecting anesthesia modalities.
Research conclusions
Results suggest that combining epidural anesthesia with multi-mode analgesia may lead to improved postoperative pain management in patients with colorectal cancer compared to general anesthesia alone. This finding emphasizes the importance of optimizing anesthesia modalities to enhance patient comfort and recovery.
Research perspectives
Future research could investigate the long-term effects and potential complications associated with different anesthesia modalities coupled with multi-mode analgesia. Additionally, exploring the impact of these techniques on other surgical procedures could provide valuable insights into pain management strategies.
