Lancellotta V, Russo G, Lupattelli M, Iacco M, Perrucci E, Zucchetti C, Falcinelli L, Aristei C. Helical tomotherapy for duodenal adenocarcinoma in an elderly patient: A case report. World J Gastrointest Oncol 2017; 9(2): 94-97 [PMID: 28255431 DOI: 10.4251/wjgo.v9.i2.94]
Corresponding Author of This Article
Valentina Lancellotta, MD, Radiation Oncology Section, Department of Surgical and Biomedical Science, University of Perugia, Perugia General Hospital, Sant’Andrea delle Fratte, 06128 Perugia, Italy. valentina.lancellotta@unipg.it
Research Domain of This Article
Oncology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Oncol. Feb 15, 2017; 9(2): 94-97 Published online Feb 15, 2017. doi: 10.4251/wjgo.v9.i2.94
Helical tomotherapy for duodenal adenocarcinoma in an elderly patient: A case report
Valentina Lancellotta, Giuseppe Russo, Marco Lupattelli, Martina Iacco, Elisabetta Perrucci, Claudio Zucchetti, Lorenzo Falcinelli, Cynthia Aristei
Valentina Lancellotta, Cynthia Aristei, Radiation Oncology Section, Department of Surgical and Biomedical Sciences, University of Perugia, Perugia General Hospital, 06128 Perugia, Italy
Giuseppe Russo, Gastroenterology Division, Perugia General Hospital, 06128 Perugia, Italy
Marco Lupattelli, Elisabetta Perrucci, Lorenzo Falcinelli, Radiation Oncology Division, Perugia General Hospital, 06128 Perugia, Italy
Martina Iacco, Claudio Zucchetti, Medical Physics Unit, Perugia General Hospital, 06128 Perugia, Italy
Author contributions: All authors contributed to the acquisition of data, writing, and revision of this manuscript.
Institutional review board statement: This case report was exempt from the Institutional Review Board standard at University of Perugia in Italy.
Informed consent statement: The patient involved in this study gave her written informed consent authorizing use and disclosure of her protected health information.
Conflict-of-interest statement: All the authors have no conflicts of interest to declare.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Valentina Lancellotta, MD, Radiation Oncology Section, Department of Surgical and Biomedical Science, University of Perugia, Perugia General Hospital, Sant’Andrea delle Fratte, 06128 Perugia, Italy. valentina.lancellotta@unipg.it
Telephone: +39-07-55783614
Received: July 13, 2016 Peer-review started: July 14, 2016 First decision: August 24, 2016 Revised: September 12, 2016 Accepted: December 1, 2016 Article in press: December 2, 2016 Published online: February 15, 2017 Processing time: 176 Days and 6.5 Hours
Abstract
To evaluate the efficacy and feasibility of external beam radiotherapy (EBRT) for duodenal adenocarcinoma in an 84-year-old female who underwent EBRT (2.2 Gy/d for a total dose of 46.2 Gy) using helical tomotherapy (HT). Toxicity was evaluated on the National Cancer Institute’s common toxicity criteria (CTCAE 3.0). The patient completed the treatment without G3-G4 toxicity. After 22-mo follow-up, she is alive and well, in complete remission with no late side effects. HT seems to be feasible and effective for duodenal adenocarcinoma in old to very old patients.
Core tip: Radiotherapy is now effective and safe for old to very old patients with duodenal adenocarcinoma, thanks to better dose conformity and tissue sparing with helical tomotherapy.
