Kawasaki S, Osawa S, Sugimoto K, Uotani T, Nishino M, Yamada T, Sugimoto M, Furuta T, Ikuma M. Cecal vanishing tumor associated with cytomegalovirus infection in an immunocompetent elderly adult. World J Gastrointest Oncol 2010; 2(11): 417-420 [PMID: 21160905 DOI: 10.4251/wjgo.v2.i11.417]
Corresponding Author of This Article
Satoshi Osawa, MD, PhD, Assistant Professor, First Department of Medicine, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu 431-3192, Japan. sososawa@hama-med.ac.jp
Article-Type of This Article
Case Report
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Shinsuke Kawasaki, Satoshi Osawa, Ken Sugimoto, Takahiro Uotani, Masafumi Nishino, Takanori Yamada, Mutsuhiro Ikuma, First Department of Medicine, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu 431-3192, Japan
Mitsushige Sugimoto, Takahisa Furuta, Center for Clinical Research, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu 431-3192, Japan
Author contributions: Kawasaki S and Osawa S wrote the manuscript; Sugimoto K, Furuta T and Ikuma M contributed to the paper design and coordination; Uotani T, Nishino M, Yamada T and Sugimoto M contributed in performing the endoscopic examination and follow-up; all the authors have read and approved the final manuscript.
Correspondence to: Satoshi Osawa, MD, PhD, Assistant Professor, First Department of Medicine, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu 431-3192, Japan. sososawa@hama-med.ac.jp
Telephone: +81-53-4352261 Fax: +81-53-4349447
Received: July 1, 2010 Revised: September 14, 2010 Accepted: September 21, 2010 Published online: November 15, 2010
Abstract
Gastrointestinal involvement in cytomegalovirus (CMV) infection is well documented among immunocompromised patients and is also observed in immunocompetent individuals. The presentation of this infection can sometimes mimic those of other diseases, thus making accurate diagnosis difficult. We herein report a rare case of an immunocompetent elderly adult with gastrointestinal CMV infection that presented as a vanishing tumor at the cecum. A 76-year old man initially presented with lower abdominal pain. Colonoscopy revealed a tumorous lesion with irregular ulceration observed at the ileocecal valve. Histological findings of a biopsy specimen revealed intranuclear inclusions which were positive for CMV on immunohistochemical staining. However, this tumorous lesion disappeared within 7 wk from the initial hospital visit without any further treatment. Inflammatory pseudotumors associated with CMV infection should be considered as a differential diagnosis of tumorous lesions in the colon, even in immunocompetent adults.
