Zhang XY, Li C, Lin J, Zhou Y, Shi RZ, Wang ZY, Jiang HB, Wang YY. Intestinal obstruction caused by early stage primary ileum adenocarcinoma: A case report and review of literature. World J Gastrointest Oncol 2025; 17(4): 104919 [DOI: 10.4251/wjgo.v17.i4.104919]
Corresponding Author of This Article
Yuan-Yuan Wang, PhD, Chief Doctor, Gastrointestinal Disease Center, The First Hospital of Hebei Medical University, No. 89 Donggang Road, Shijiazhuang 050000, Hebei Province, China. 58201746@hebmu.edu.cn
Research Domain of This Article
Surgery
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Oncol. Apr 15, 2025; 17(4): 104919 Published online Apr 15, 2025. doi: 10.4251/wjgo.v17.i4.104919
Intestinal obstruction caused by early stage primary ileum adenocarcinoma: A case report and review of literature
Xiao-Yue Zhang, Chao Li, Jie Lin, Yan Zhou, Rui-Zhe Shi, Zhong-Yu Wang, Hai-Bo Jiang, Yuan-Yuan Wang
Xiao-Yue Zhang, Chao Li, Jie Lin, Yan Zhou, Rui-Zhe Shi, Zhong-Yu Wang, Hai-Bo Jiang, Yuan-Yuan Wang, Gastrointestinal Disease Center, The First Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China
Co-first authors: Xiao-Yue Zhang and Chao Li.
Author contributions: Zhang XY and Li C contributed equally to this work; Zhang XY and Li C contributed to conception; Lin J and Zhou Y contributed to collection and assembly of data; Shi RZ and Wang ZY contributed to data analysis and interpretation; Jiang HB and Wang YY contributed to writing and figure preparation; Wang YY contributed to review and editing; All authors have read and agreed to the published version of the manuscript.
Informed consent statement: Informed written consent was obtained from the patient for the publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yuan-Yuan Wang, PhD, Chief Doctor, Gastrointestinal Disease Center, The First Hospital of Hebei Medical University, No. 89 Donggang Road, Shijiazhuang 050000, Hebei Province, China. 58201746@hebmu.edu.cn
Received: January 9, 2025 Revised: February 6, 2025 Accepted: February 25, 2025 Published online: April 15, 2025 Processing time: 78 Days and 14 Hours
Abstract
BACKGROUND
Ileum adenocarcinoma (IA), a type of small bowel adenocarcinoma, is a rather uncommon factor associated with obstruction in small bowel. Owing to its location and indefinite clinical symptoms, the diagnosis of IA is difficult, and survival is usually poor. With respect to the rarity of this disease, very few studies have reported such cases to provide a reference for treatment.
CASE SUMMARY
In this manuscript, a case of a 48-year-old man presented with chronic right lower abdominal pain and distention, queasiness and emesis. A computed tomography scan revealed intestinal wall thickening and an intestinal obstruction in the terminal ileum. He was diagnosed with inflammatory bowel disease. However, his symptoms were not relieved after conservative treatment. The patient subsequently underwent exploratory laparotomy, and a tumour in the ileum measuring approximately 2.0 cm × 2.0 cm that was located 20 cm from the ileocolic valve was discovered incidentally and was operatively resected along with the enlarged lymph nodes. Pathological examination revealed a stage IIA (T3N0M0) ulcerative IA. Along with imaging examinations, a diagnosis of primary IA with no lymph or distant metastases was considered. The patient was discharged and recovered well as of the writing of this manuscript.
CONCLUSION
IA should be considered as a differential diagnosis in cases of intestinal obstruction, and the recommended method for local disease treatment is surgery.
Core Tip: Adenocarcinoma in the ileum is an extremely rare pathological type. Its clinical presentation is indefinite, and its diagnosis is challenging. Here, the case of a 48-year-old man who was diagnosed with primary ileum adenocarcinoma was presented. Proper diagnosis and early intervention are important for the prognosis of patients. For local disease, surgical excision along with the removal of regional lymph nodes en bloc is recommended.
