Sapkota A, Paudel R, Pandey S, Bhatt N. Solid pseudopapillary neoplasm of the pancreas in an adolescent: A case report and review of the literature. World J Gastrointest Oncol 2025; 17(3): 101859 [DOI: 10.4251/wjgo.v17.i3.101859]
Corresponding Author of This Article
Aakriti Sapkota, MBBS, Doctor, Department of Medicine, B.P. Koirala Institute of Health Sciences, Buddha Road, Dharan 56700, Koshi, Nepal. sapkota.aakriti5@gmail.com
Research Domain of This Article
Oncology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Aakriti Sapkota, Sandip Pandey, Department of Medicine, B.P. Koirala Institute of Health Sciences, Dharan 56700, Koshi, Nepal
Rajesh Paudel, Department of Radiodiagnosis and Imaging, B.P. Koirala Institute of Health Sciences, Dharan 56700, Koshi, Nepal
Navin Bhatt, Department of Medicine, NYC Health + Hospitals/Elmhurst, Icahn School of Medicine at Mount Sinai, Elmhurst, NY 11373, United States
Author contributions: Sapkota A and Paudel R designed this study; Paudel R provided study materials; Sapkota A, Pandey S, and Bhatt N collected and analyzed the data. All authors contributed to manuscript writing and collectively approved the final version.
Informed consent statement: All authors take full responsibility for all aspects of the work, ensuring that any inquiries regarding the accuracy or integrity of any part of the study are thoroughly investigated and addressed. Informed written consent was obtained from the patient’s guardian to publish this case report and the associated images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Aakriti Sapkota, MBBS, Doctor, Department of Medicine, B.P. Koirala Institute of Health Sciences, Buddha Road, Dharan 56700, Koshi, Nepal. sapkota.aakriti5@gmail.com
Received: September 28, 2024 Revised: November 27, 2024 Accepted: December 19, 2024 Published online: March 15, 2025 Processing time: 138 Days and 17.6 Hours
Abstract
BACKGROUND
Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare epithelial tumor that primarily affects young women. Since the condition is often asymptomatic or presents with non-specific symptoms, its diagnosis can be difficult.
CASE SUMMARY
This report details the case of a 15-year-old girl who presented with a 2-year history of abdominal pain, with no significant findings during physical examination. Abdominal ultrasound revealed a well-defined heterogeneous solid-cystic mass in the epigastric region, likely originating from the tail of the pancreas. A subsequent contrast-enhanced computed tomography scan indicated a well-defined cystic lesion with an enhancing solid component and capsule in the tail of the pancreas, suggestive of a cystic neoplasm. The patient underwent an open distal pancreatectomy with splenectomy, and histopathological analysis confirmed the diagnosis of SPN of the pancreas.
CONCLUSION
This case highlights the risk of SPN in adolescent girls and the necessity of early diagnosis and intervention for better outcomes.
Core Tip: Solid pseudopapillary neoplasm (SPN) of the pancreas is an uncommon pancreatic tumor that primarily impacts young women, especially those in their twenties and thirties. This report highlights the case of a 15-year-old female patient who experienced a two-year history of abdominal pain and was diagnosed with a solid pseudopapillary neoplasm localized to the pancreatic tail. The patient underwent an open distal pancreatectomy accompanied by splenectomy, and histopathological examination confirmed the diagnosis of SPN. This case underscores the possibility of SPN occurring in adolescent girls and points out the vital importance of early diagnosis and timely intervention, which can significantly enhance clinical outcomes.
