Li DH, Feng RQ. Modern technology-based exploration of mechanism of traditional Chinese medicine in prevention and treatment of gastric cancer. World J Gastrointest Oncol 2024; 16(9): 3747-3751 [DOI: 10.4251/wjgo.v16.i9.3747]
Corresponding Author of This Article
De-Hui Li, MD, Doctor, Oncology Department II, The First Affiliated Hospital of Hebei University of Chinese Medicine (Hebei Province Hospital of Chinese Medicine), Key Laboratory of Integrated Chinese and Western Medicine for Gastroenterology Research, No. 389 Zhongshan East Road, Chang’an District, Shijiazhuang 050000, Hebei Province, China. 258289951@qq.com
Research Domain of This Article
Oncology
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Oncol. Sep 15, 2024; 16(9): 3747-3751 Published online Sep 15, 2024. doi: 10.4251/wjgo.v16.i9.3747
Modern technology-based exploration of mechanism of traditional Chinese medicine in prevention and treatment of gastric cancer
De-Hui Li, Rui-Qi Feng
De-Hui Li, Oncology Department II, The First Affiliated Hospital of Hebei University of Chinese Medicine (Hebei Province Hospital of Chinese Medicine), Key Laboratory of Integrated Chinese and Western Medicine for Gastroenterology Research, Shijiazhuang 050000, Hebei Province, China
Rui-Qi Feng, Graduate School, Hebei University of Chinese Medicine, Shijiazhuang 050000, Hebei Province, China
Author contributions: Both Li DH and Feng RQ have made contributions to this article; Li DH designed the overall concept and outline of the manuscript; Li DH and Feng RQ contributed to the writing and editing of the manuscript, and the review of the literature; and all authors have read and approved the final manuscript.
Supported by2023 Government-funded Project of the Outstanding Talents Training Program in Clinical Medicine, No. ZF2023165; and Key Research and Development Projects of Hebei Province, No. 18277731D.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: De-Hui Li, MD, Doctor, Oncology Department II, The First Affiliated Hospital of Hebei University of Chinese Medicine (Hebei Province Hospital of Chinese Medicine), Key Laboratory of Integrated Chinese and Western Medicine for Gastroenterology Research, No. 389 Zhongshan East Road, Chang’an District, Shijiazhuang 050000, Hebei Province, China. 258289951@qq.com
Received: March 10, 2024 Revised: May 12, 2024 Accepted: June 4, 2024 Published online: September 15, 2024 Processing time: 183 Days and 3 Hours
Abstract
This review comments on the article “To explore the mechanism of Yigong San anti-gastric cancer and immune regulation”. We are interested that the article applied network pharmacology and bioinformatics techniques to elucidate the mechanism of action of Yigong Sang, a traditional Chinese medicine (TCM), in the treatment of gastric cancer (GC). The mechanism of action of Yigong Sang in the treatment of GC has not yet been elucidated because it is composed of multiple Chinese medicines with multiple components and multiple targets. The emergence of network pharmacology and bioinformatics analysis helps explain the mechanism of action of TCM in preventing and treating GC, and provides a possibility for TCM to transform from empirical to evidence-based medicine. This is of great significance for the application of TCM in oncology, new drug development, formula optimization, and the improvement of clinical efficacy.
Core Tip: In this editorial, we explore the importance of traditional Chinese medicine (TCM) in the prevention and treatment of malignant tumors, as well as the important role played by emerging technologies such as network pharmacology and bioinformatics in understanding the mechanism of action of TCMs. These techniques have not only accelerated the research and elucidation of the mechanism of action of TCM in the prevention and treatment of malignant tumors, but they have also promoted the modernization and standardization of TCM.
