Yu PP, Liu XC, Yin L, Yin G. Aggressive fibromatosis of the sigmoid colon: A case report. World J Gastrointest Oncol 2024; 16(8): 3716-3722 [PMID: 39171176 DOI: 10.4251/wjgo.v16.i8.3716]
Corresponding Author of This Article
Guang Yin, MD, Doctor, Department of Gastrointestinal and Anal Surgery, The Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, No. 261 Huansha Road, Hangzhou 310006, Zhejiang Province, China.yin_guang@aliyun.com
Research Domain of This Article
Oncology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Oncol. Aug 15, 2024; 16(8): 3716-3722 Published online Aug 15, 2024. doi: 10.4251/wjgo.v16.i8.3716
Aggressive fibromatosis of the sigmoid colon: A case report
Pan-Pan Yu, Xin-Chun Liu, Lu Yin, Guang Yin
Pan-Pan Yu, Xin-Chun Liu, Guang Yin, Department of Gastrointestinal and Anal Surgery, The Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou 310006, Zhejiang Province, China
Pan-Pan Yu, Department of Gastric Surgery, Zhejiang Cancer Hospital, Hangzhou 310022, Zhejiang Province, China
Lu Yin, Department of Pathology, The Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou 310006, Zhejiang Province, China
Author contributions: Yu PP and Yin G designed the study; Liu XC and Yu PP treated the patient and collected the data; Liu XC and Yin G collected and analyzed the data; Liu XC and Yin L wrote the original draft; Yin G and Yu PP reviewed and edited the manuscript; All authors have read and approved the submitted version.
Supported byHangzhou Health Science and Technology Program, No. A20210271.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read CARE Checklist (2016), and the manuscript was prepared and revised according to CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Guang Yin, MD, Doctor, Department of Gastrointestinal and Anal Surgery, The Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, No. 261 Huansha Road, Hangzhou 310006, Zhejiang Province, China.yin_guang@aliyun.com
Received: March 13, 2024 Revised: June 8, 2024 Accepted: July 2, 2024 Published online: August 15, 2024 Processing time: 147 Days and 21.2 Hours
Abstract
BACKGROUND
Aggressive fibromatosis (AF), also known as desmoid tumor or desmoid-type fibromatosis, is a rare soft tissue neoplasm that can occur in almost any part of the body. Although it is a benign disease, AF is aggressive and infiltrative and has a high recurrence rate after surgery. Common sites for intra-abdominal AF are the small bowel mesentery, retroperitoneum, and pelvis. AF in the colon is extremely rare.
CASE SUMMARY
Here, we report the first case of sigmoid colon AF, which was accidentally discovered in a 27-year-old woman during laparoscopic myomectomy. Computed tomography confirmed a slightly enhanced mass in the sigmoid colon. Subsequent colonoscopy did not reveal a mass in the colonic lumen, but a suspected external compress was found in the sigmoid colon. Surgical disease involving a gastrointestinal stromal tumor was suspected. The patient underwent laparoscopic exploration, and sigmoidectomy with a negative margin was performed to excise the mass. Postoperative immunohistochemistry revealed that the mass was an AF. The patient recovered well and was recurrence-free at the 30-month follow-up without adjuvant therapy.
CONCLUSION
AF should be considered in the differential diagnosis of subepithelial colon masses. Radical resection alone can achieve good outcomes.
Core Tip: Aggressive fibromatosis (AF) is a rare soft tissue neoplasm that can occur in almost any part of the body. Here, we report the first case of sigmoid colon AF, which was accidentally discovered in a 27-year-old woman during laparoscopic myomectomy. The patient underwent laparoscopic exploration, and sigmoidectomy with a negative margin was performed to excise the mass. Postoperative immunohistochemistry revealed that the mass was an AF. The patient recovered well and was recurrence-free at the 30-month follow-up without adjuvant therapy. AF should be considered in the differential diagnosis of subepithelial colon masses.
