Published online Jul 15, 2024. doi: 10.4251/wjgo.v16.i7.3350
Revised: May 6, 2024
Accepted: May 21, 2024
Published online: July 15, 2024
Processing time: 103 Days and 3.3 Hours
The incidence of multiple primary carcinomas (MPC) varies greatly, ranging from 0.73% to 11.70% in foreign countries, with duo-duplex carcinoma being the most common, trio-duplex carcinoma and above being rare, and simultaneous multigenic carcinoma being even rarer, accounting for 18.4% to 25.3% of the incidence of MPC. However, there is no report regarding patients presenting with simultaneous dual-origin carcinoma of the liver and colon and heterochronous pancreatic cancer.
We report a special case of multifocal carcinoma, in which one patient had a medical condition of primary liver and colon cancer and pancreatic cystadenocarcinoma 2 years after surgery. Through aggressive advanced fluorescent laparoscopic techniques, standardized immunotherapy, targeting, and chemotherapy, a better prognosis and a desirable survival period were achieved for the patient.
There is a need to clarify the nature of MPC through advanced surgical means to ensure better diagnosis and treatment.
Core Tip: This study describes an uncommon case of simultaneous dual-origin carcinoma of the liver and colon and heterochronous pancreatic cancer, which was verified through histopathological and immunohistochemical analyses. Our findings suggest that patients can benefit from comprehensive diagnosis and treatment.