Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jul 15, 2024; 16(7): 2877-2880
Published online Jul 15, 2024. doi: 10.4251/wjgo.v16.i7.2877
Can the preoperative prognostic nutritional index be used as a postoperative predictor of gastric or gastroesophageal junction adenocarcinoma?
Yu-Wei Feng, Hai-Ying Wang, Qiang Lin
Yu-Wei Feng, Hai-Ying Wang, Department of Nursing, North China Petroleum Bureau General Hospital, Hebei Medical University, Cangzhou 062552, Hebei Province, China
Qiang Lin, Department of Oncology, North China Petroleum Bureau General Hospital, Hebei Medical University, Cangzhou 062552, Hebei Province, China
Author contributions: Feng YW wrote the manuscript; Wang HY reviewed the data; and Lin Q provided comprehensive guidance on the manuscript. All authors have read and approved the final manuscript.
Conflict-of-interest statement: All authors have nothing to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qiang Lin, MD, PhD, Professor, Department of Oncology, North China Petroleum Bureau General Hospital, Hebei Medical University, No. 8 Huizhan Avenue, Cangzhou 062552, Hebei Province, China. billhappy001@163.com
Received: February 9, 2024
Revised: April 25, 2024
Accepted: May 15, 2024
Published online: July 15, 2024
Processing time: 154 Days and 6.7 Hours
Abstract

Gastric cancer and adenocarcinoma of the esophagogastric junction are major challenges to global public health due to their high morbidity and mortality. Despite continuous improvements in treatment techniques, patient prognosis is still affected by multiple factors. The preoperative prognostic nutritional index (PNI), a simple clinical indicator, has received widespread attention in recent years. Fiflis et al conducted a systematic review and reported that a high PNI was associated with significantly better survival in patients with gastric cancer. They also found that the PNI had prognostic value in patients with cancer of different TNM stages and had a positive effect even in advanced gastric cancer patients. Although the study did not address the impact of treatment regimens and had limited data sources, the results support the validity of the PNI as a biomarker for predicting the survival of gastric cancer patients. Future studies should further standardize the calculation method of the PNI, explore its applicability in different populations, and integrate other clinical parameters to construct more accurate prediction models.

Keywords: Gastric cancer; Adenocarcinoma of the esophagogastric junction; Preoperative nutritional index; Systematic review; Clinical indicators

Core Tip: Despite continuous improvement in treatment techniques, patient prognosis with gastric cancer and adenocarcinoma of the esophageal junction is still affected by multiple factors. Fiflis et al conducted a systematic review and found that a high the prognostic nutritional index (PNI) was associated with significantly better survival in patients with gastric cancer. The results provide support for the validity of PNI as a biomarker in predicting the survival of gastric cancer patients. Future studies should further standardize the calculation method of PNI, explore its applicability in different populations, and integrate other clinical parameters to construct more accurate prediction models.