Sun KK, Wu YY. Pylorus-preserving gastrectomy for early gastric cancer. World J Gastrointest Oncol 2024; 16(3): 653-658 [PMID: 38577445 DOI: 10.4251/wjgo.v16.i3.653]
Corresponding Author of This Article
Yong-You Wu, FRCS (Ed), MD, MM, PhD, Chief Doctor, Director, Professor, Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Soochow University, No. 1055 Sanxiang Road, Suzhou 215008, Jiangsu Province, China. wuyongyou72@126.com
Research Domain of This Article
Oncology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Oncol. Mar 15, 2024; 16(3): 653-658 Published online Mar 15, 2024. doi: 10.4251/wjgo.v16.i3.653
Pylorus-preserving gastrectomy for early gastric cancer
Ke-Kang Sun, Yong-You Wu
Ke-Kang Sun, Department of Gastrointestinal Surgery, The Affiliated Kunshan Hospital to Jiangsu University, Suzhou 215300, Jiangsu Province, China
Yong-You Wu, Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Soochow University, Suzhou 215008, Jiangsu Province, China
Author contributions: Sun KK performed the research and wrote the paper; Wu YY designed the research and and approved the final manuscript.
Conflict-of-interest statement: All the Authors have no conflict of interest related to the manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yong-You Wu, FRCS (Ed), MD, MM, PhD, Chief Doctor, Director, Professor, Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Soochow University, No. 1055 Sanxiang Road, Suzhou 215008, Jiangsu Province, China. wuyongyou72@126.com
Received: December 21, 2023 Peer-review started: December 21, 2023 First decision: January 10, 2024 Revised: January 15, 2024 Accepted: February 6, 2024 Article in press: February 6, 2024 Published online: March 15, 2024 Processing time: 82 Days and 1.6 Hours
Abstract
Pylorus-preserving gastrectomy (PPG) has been widely accepted as a function-preserving gastrectomy for middle-third early gastric cancer (EGC) with a distal tumor border at least 4 cm proximal to the pylorus. The procedure essentially preserves the function of the pyloric sphincter, which requires to preserve the upper third of the stomach and a pyloric cuff at least 2.5 cm. The suprapyloric and infrapyloric vessels are usually preserved, as are the hepatic and pyloric branches of the vagus nerve. Compared with distal gastrectomy, PPG has significant advantages in preventing dumping syndrome, body weight loss and bile reflux gastritis. The postoperative complications after PPG have reached an acceptable level. PPG can be considered a safe, effective, and superior choice in EGC, and is expected to be extensively performed in the future.
Core Tip: Pylorus-preserving gastrectomy (PPG) has been widely accepted as a function-preserving gastrectomy for middle-third early gastric cancer. The procedure requires to preserve the upper third of the stomach and a pyloric cuff at least 2.5 cm. The hepatic and pyloric branches of the vagus nerve are usually preserved. PPG has significant advantages in preventing dumping syndrome, body weight loss and bile reflux gastritis.