Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jan 15, 2024; 16(1): 110-117
Published online Jan 15, 2024. doi: 10.4251/wjgo.v16.i1.110
Clinical value of oral contrast-enhanced ultrasonography in diagnosis of gastric tumors
Chuan-Yu Wang, Xiao-Jing Fan, Fei-Liang Wang, Yue-Yue Ge, Zhao Cai, Wei Wang, Xin-Ping Zhou, Jun Du, De-Wei Dai
Chuan-Yu Wang, Xiao-Jing Fan, Fei-Liang Wang, Yue-Yue Ge, Zhao Cai, De-Wei Dai, Department of Ultrasound Medicine, Beijing Hospital, Beijing 100005, China
Wei Wang, Department of Gastroscopy, Beijing Hospital, Beijing 100005, China
Xin-Ping Zhou, Department of General Surgery, Beijing Hospital, Beijing 100005, China
Jun Du, Department of Pathology, Beijing Hospital, Beijing 100005, China
Author contributions: Wang CY and Dai DW designed the research study; Wang CY, Fan XJ, and Wang FL performed the research; Wang CY, Fan XJ, Wang FL, Ge YY, Cai Z, Wang W, Zhou XP, Du J, and Dai DW analyzed the data and wrote the manuscript; all authors have read and approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Beijing Hospital Institutional Review Board.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: There is no conflict of interest to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: De-Wei Dai, MD, Chief Physician, Department of Ultrasound Medicine, Beijing Hospital, No. 1 Dahua Road, Dongdan, Dongcheng District, Beijing 100005, China. dai.weide@126.com
Received: September 14, 2023
Peer-review started: September 14, 2023
First decision: October 8, 2023
Revised: November 10, 2023
Accepted: November 15, 2023
Article in press: November 15, 2023
Published online: January 15, 2024
Processing time: 114 Days and 20.8 Hours
Abstract
BACKGROUND

The incidence of gastric cancer remains high, and it is the sixth most common cancer and the fourth leading cause of cancer deaths worldwide. Oral contrast-enhanced ultrasonography is a simple, non-invasive, and painless method for the diagnosis of gastric tumors.

AIM

To explore the diagnostic value of oral contrast-enhanced ultrasonography for the detection of gastric tumors.

METHODS

The screening results based on oral contrast-enhanced ultrasonography and electronic gastroscopy were compared with those of the postoperative pathological examination.

RESULTS

Among 42 patients with gastric tumors enrolled in the study, the diagnostic accordance rate was 95.2% for oral contrast-enhanced ultrasonography (n = 40) and 90.5% for electronic gastroscopy (n = 38) compared with postoperative pathological examination. The Kappa value of consistency test with pathological findings was 0.812 for oral contrast-enhanced ultrasonography and 0.718 for electronic gastroscopy, and there was no significant difference between them (P = 0.397). For the TNM staging of gastric tumors, the accuracy rate of oral contrast-enhanced ultrasonography was 81.9% for the overall T staging and 50%, 77.8%, 100%, and 100% for T1, T2, T3, and T4 staging, respectively. The sensitivity and specificity were both 100% for stages T3 and T4. The diagnostic accuracy rate of oral contrast-enhanced ultrasonography was 93.8%, 80%, 100%, and 100% for stages N0, N1-N3, M0, and M1, respectively.

CONCLUSION

The accordance rate of qualitative diagnosis by oral contrast-enhanced ultrasonography is comparable to that of gastroscopy, and it could be used as the preferred method for the early screening of gastric tumors.

Keywords: Oral contrast-enhanced ultrasonography; Gastric tumor; Electronic gastroscopy; Controlled study; Pathological examination; Diagnosis

Core Tip: In this study, a total of 42 gastric tumor patients underwent both oral contrast-enhanced ultrasonography and gastroscopy. The diagnostic findings and the postoperative pathological examination results were compared to evaluate the diagnostic value of oral contrast-enhanced ultrasonography for the diagnosis of gastric tumors.