Case Report
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Nov 15, 2023; 15(11): 2041-2048
Published online Nov 15, 2023. doi: 10.4251/wjgo.v15.i11.2041
Pancreatic pseudoaneurysm mimicking pancreatic tumor: A case report and review of literature
Yuan Yang, Xue-Mei Liu, Hong-Ping Li, Rui Xie, Bi-Guang Tuo, Hui-Chao Wu
Yuan Yang, Xue-Mei Liu, Hong-Ping Li, Rui Xie, Bi-Guang Tuo, Hui-Chao Wu, Department of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou Province, China
Author contributions: Yang Y drafted the manuscript and collected data; Liu XM and Li HP diagnosed the patient; Xie R and Wu HC performed the operation; Tuo BG and Wu HC guided the operation and revised the manuscript; All authors have approved the final draft submitted.
Supported by Guizhou Provincial Basic Research Program (Natural Science), No. QIAN KE HE JI CHU-ZK (2023) YI BAN 558; Collaborative Innovation Center of Chinese Ministry of Education, No. 2020-39.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hui-Chao Wu, MD, Chief Physician, Professor, Department of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University, No. 149 Dalian Road, Zunyi 563000, Guizhou Province, China. wuhuichao985@163.com
Received: August 31, 2023
Peer-review started: August 31, 2023
First decision: September 23, 2023
Revised: October 4, 2023
Accepted: October 23, 2023
Article in press: October 23, 2023
Published online: November 15, 2023
Processing time: 76 Days and 8 Hours
Abstract
BACKGROUND

Pancreatic pseudoaneurysm is a rare vascular complication of chronic pancreatitis (CP) or necrotizing pancreatitis with an incidence of 4% to 17%, but it is potentially life-threatening. It is well known that most pancreatic pseudoaneurysms are clinically associated with pancreatic pseudocysts and are usually in the peripancreatic body-tail. A minority of intrapancreatic pseudoaneurysms occur in the absence of pseudocyst formation. Noninvasive computed tomography (CT) and magnetic resonance imaging (MRI) are most commonly used examinations for screening pancreatic pseudoaneurysms. Notably, the rare intrapancreatic pseudoaneurysm in the pancreatic head can mimic a hypervascular solid mass and be misdiagnosed as a pancreatic tumor.

CASE SUMMARY

We report the case of a 67-year-old man who had been admitted to our hospital due to recurrent abdominal pain for 1 mo that was aggravated for 5 d. CT and MRI revealed a mass in the pancreatic head with significant expansion of the main pancreatic duct and mild atrophy of the pancreatic body-tail. He was admitted to the department of hepatobiliary and pancreatic surgery due to the possibility of a pancreatic tumor. The patient was then referred for endoscopic ultrasonography (EUS) with possible EUS-FNA. However, EUS showed a cystic lesion in the pancreatic head with wall thickness and enhancing nodules, which was doubtful because it was inconsistent with the imaging findings. Subsequently, color doppler flow imaging demonstrated turbulent arterial blood flow in the cystic lesion and connection with the surrounding vessel. Therefore, we highly suspected the possibility of CP complicated with intrapancreatic pseudoaneurysm, combined with the patient's long-term drinking history and the sonographic features of CP. Indeed, angiography revealed an oval area of contrast medium extravasation (size: 1.0 cm × 1.5 cm) at the far-end branch of the superior pancreaticoduodenal artery, and angiographic embolization was given immediately at the same time.

CONCLUSION

EUS is an important differential diagnostic tool when pancreatic pseudoaneurysm mimics the imaging appearance of a hypervascular pancreatic tumor.

Keywords: Pancreatic pseudoaneurysm; Chronic pancreatitis; Pancreaticoduodenal artery; Endoscopic ultrasonography; Case report

Core Tip: Pancreatic pseudoaneurysm is a rare vascular complication of chronic pancreatitis, and the most commonly used clinical screening methods are computed tomography (CT) and magnetic resonance imaging (MRI). We report an even rarer case of an intrapancreatic pseudoaneurysm that mimicked a pancreatic neuroendocrine tumor on the axial view of contrast-enhanced CT and MRI. Finally, the diagnosis was confirmed by endoscopic ultrasonography; the patient was successfully treated with angiographic embolization. The imaging findings of pancreatic pseudoaneurysm mimicking pancreatic tumor is a concern.