Randomized Controlled Trial
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jun 15, 2022; 14(6): 1187-1198
Published online Jun 15, 2022. doi: 10.4251/wjgo.v14.i6.1187
Biofeedback therapy combined with Baduanjin on quality of life and gastrointestinal hormone level in patients with colorectal cancer
Xiao-Ding Zhou, Hong-Gang Wei, Fu-Lu Ai
Xiao-Ding Zhou, Graduate Work Department, Shenyang Sport University, Shenyang 110102, Liaoning Province, China
Hong-Gang Wei, Wushu and Dance Academy, Shenyang Sport University, Shenyang 110115, Liaoning Province, China
Fu-Lu Ai, Department of General Surgery, Liaoning Tumor Hospital, Shenyang 110042, Liaoning Province, China
Author contributions: Zhou XD performed the experiments and wrote the manuscript; Wei HG helped perform the data analysis with constructive discussions; Ai FL contributed significantly to data analysis and manuscript preparation.
Institutional review board statement: The study was reviewed and approved by the Liaoning Tumor Hospital Institutional Review Board.
Informed consent statement: All participants gave informed consent for data sharing.
Conflict-of-interest statement: There is no conflict of interest in this study.
Data sharing statement: The original data can be obtained from the corresponding author’s email address (weihonggang369@163.com).
CONSORT 2010 statement: The authors have read the CONSORT 2010 statement, and the manuscript was prepared and revised according to the CONSORT 2010 statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hong-Gang Wei, MSc, Lecturer, Wushu and Dance Academy, Shenyang Sport University, No. 36 Jinqiansong East Road, Sujiatun District, Shenyang 110115, Liaoning Province, China. weihonggang369@163.com
Received: January 24, 2022
Peer-review started: January 24, 2022
First decision: March 13, 2022
Revised: March 15, 2022
Accepted: May 16, 2022
Article in press: May 16, 2022
Published online: June 15, 2022
Processing time: 136 Days and 19 Hours
Abstract
BACKGROUND

With the change in people’s lifestyles, the incidence of colorectal cancer (CRC) is increasing. It is essential to study the efficacy of various treatment methods for CRC patients to prevent and treat CRC.

AIM

To investigate the efficacy of biofeedback therapy combined with Baduanjin in improving the quality of life and gastrointestinal hormone levels of patients with CRC.

METHODS

A total of 120 patients with CRC who were admitted to our hospital from June 2020 to June 2021 were included in the study. They were randomly divided into four groups (n = 30): the control group (group A), the biofeedback therapy intervention group (group B), the Baduanjin exercise intervention group (group C), and the combination group (group D). Patients in group A adopted the standard nursing mode and necessary health education. Patients in group B were treated with biofeedback therapy based on routine nursing care. Patients in group C were given Baduanjin intervention for 12 wk based on conventional drug treatment and care. Patients in group D were treated with biofeedback therapy and Baduanjin exercise. In this study, patients’ quality of life, gastrointestinal hormone levels, and clinical efficacy in the four groups were observed at baseline and 12 wk after intervention. Meanwhile, the correlation between gastrointestinal hormone levels and various functional areas of quality of life was analyzed. By comparing the observed indicators of patients in the four groups, the efficacy of biofeedback therapy combined with Baduanjin in improving the quality of life and gastrointestinal hormone levels of patients with CRC was explored.

RESULTS

At baseline, there were no significant differences in quality of life, gastrointestinal hormone levels, or clinical efficacy among the four groups (P > 0.05). Twelve weeks after the intervention, the combination group’s quality of life, gastrointestinal hormone levels, and clinical effectiveness were better than those of the three other groups.

CONCLUSION

On the basis of routine nursing care, patients with CRC combined with biofeedback therapy and Baduanjin exercise can improve the quality of life of patients with CRC and the efficacy of gastrointestinal hormone levels.

Keywords: Biofeedback therapy; Baduanjin; Colorectal cancer; Quality of life; Gastrointestinal hormone level; Clinical efficacy

Core Tip: With the increasing incidence and recurrence rate of colorectal cancer (CRC), it is essential to study more comprehensive measures for its treatment and prevention, such as cognitive-behavioral intervention, exercise intervention, and the combination of biofeedback therapy. In this study, CRC patients were treated with 12 wk of biofeedback therapy combined with Baduanjin exercise intervention training to observe the changes in patients’ quality of life and gastrointestinal hormone levels and to explore the clinical value of biofeedback therapy combined with Baduanjin exercise from the overall perspective, which will be vital for the future research on the treatment strategies of CRC.