Letter to the Editor
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Sep 15, 2021; 13(9): 1210-1212
Published online Sep 15, 2021. doi: 10.4251/wjgo.v13.i9.1210
Use of liquid biopsies in gastrointestinal cancers
Hussein H Khachfe
Hussein H Khachfe, Department of Gastrointestinal Surgical Oncology, University of Pittsburgh, Pittsburgh, PA 15232, United States
Author contributions: Khachfe HH performed the research, wrote, and revised the letter.
Conflict-of-interest statement: The author does not report any conflict of interest. The author did not receive any funding.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hussein H Khachfe, MD, Doctor, Research Fellow, Department of Gastrointestinal Surgical Oncology, University of Pittsburgh, 3550 Terrace St, Pittsburgh, PA 15232, United States. hhk15@mail.aub.edu
Received: May 8, 2021
Peer-review started: May 8, 2021
First decision: June 16, 2021
Revised: June 16, 2021
Accepted: August 9, 2021
Article in press: August 9, 2021
Published online: September 15, 2021

The use of liquid biopsies is a relatively new tool in diagnosis and management of gastrointestinal cancers and is actively being investigated. Liquid biopsies have become extremely popular in cholangiocarcinoma and pancreatic cancer research. With more prospective trials using this tool for early diagnosis, liquid biopsies may become an important part of cancer management.

Keywords: Liquid biopsy, Gastrointestinal cancer, Cholangiocarcinoma, Pancreatic cancer

Core Tip: Liquid biopsies are a novel method to help physicians in the early diagnosis and management of various cancer subtypes. Due to the east of performance, cost-effectiveness, and quick results associated with liquid biopsies, this technique will be integrated more into the treatment of aggressive cancer types such as cholangiocarcinoma and pancreatic cancers. More prospective clinical trials are needed to validate results on this tool.