Case Report
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Feb 16, 2017; 9(2): 85-90
Published online Feb 16, 2017. doi: 10.4253/wjge.v9.i2.85
Over-the-scope-clip closure of long lasting gastrocutaneous fistula after percutaneous endoscopic gastrostomy tube removal in immunocompromised patients: A single center case series
Henriette Heinrich, Christoph Gubler, Piero V Valli
Henriette Heinrich, Christoph Gubler, Piero V Valli, Division of Gastroenterology and Hepatology, University Hospital Zurich, CH-8091 Zurich, Switzerland
Author contributions: All the authors contributed to the manuscript.
Institutional review board statement: A general institutional review board statement for the Department of Gastroenterology and Hepatology issued by the Zuerich Ethics comittee was in place for conducting this case series report.
Informed consent statement: Written consent for the endoscopy as well as research with their medical records was obtained from each patient.
Conflict-of-interest statement: The authors declare no conflicts of interest regarding this manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Christoph Gubler, MD, Division of Gastroenterology and Hepatology, University Hospital Zurich, Raemistrasse 100, CH-8091 Zurich, Switzerland. christoph.gubler@icloud.com
Telephone: +41-44-2553642 Fax: +41-44-2554474
Received: July 5, 2016
Peer-review started: July 12, 2016
First decision: September 9, 2016
Revised: October 8, 2016
Accepted: November 21, 2016
Article in press: November 22, 2016
Published online: February 16, 2017
Processing time: 224 Days and 12.7 Hours
Core Tip

Core tip: Over-the-scope-clips (OTSC®) are effective and safe for closure of gastrointestinal perforations, leakages and fistulae. There is growing evidence that OTSC® can be applied for the closure of gastro-cutaneous fistula after percutaneous endoscopic gastrostomy (PEG) tube removal. In this retrospective single-center case-series we report on five middle-aged patients with multiple comorbidities undergoing OTSC® closure of chronic gastro cutaneous fistula after PEG tube removal. The mean dwell time of PEG tubes was 808 d. Successful immediate and long-term fistula closure was accomplished in all five patients. OTSC® is a promising treatment for this condition with a high immediate and long-term success rate.