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World J Gastrointest Endosc. Sep 16, 2013; 5(9): 446-449
Published online Sep 16, 2013. doi: 10.4253/wjge.v5.i9.446
Published online Sep 16, 2013. doi: 10.4253/wjge.v5.i9.446
Extremely rare case of primary esophageal mucous associated lymphoid tissue lymphoma
Ali Osama Malik, Department of Medicine, Robert Wood Johnson University Hospital, Hamilton, NJ 08540, United States
Ali Osama Malik, Department of Cardiovascular Medicine Cleveland Clinic Foundation, Cleveland, OH 44120, United States
Zahid Baig, Department of Medicine, Robert Wood Johnson University Hospital, Hamilton, NJ 08540, United States
Aqeel Ahmed, Department of Pathology, Columbia Presbytirian Hospital, New York, NY 10259, United States
Nasar Qureshi, Department of Pathology QD, Pathology Services, Cranford, NJ 07016, United States
Fatima Noor Malik, Department of Medicine, Robert Wood Johnson University Hospital, Hamilton, NJ 08540, United States
Author contributions: Malik AO and Baig Z wrote the manuscript; Ahmed A and Qureshi N provided feedback on the manuscript and the staining of the biopsy samples; Malik FN provided valuable contribution to the manuscript and also did the conversion of the figures into the required format.
Correspondence to: Dr. Ali Osama Malik, Department of Cardiovascular Medicine Cleveland Clinic Foundation, Euclid Avenue, Cleveland, OH 44120, United States. a_o_malik@hotmail.com
Telephone: +1-609-3720251 Fax: +1-609-3720251
Received: May 24, 2013
Revised: July 18, 2013
Accepted: August 4, 2013
Published online: September 16, 2013
Revised: July 18, 2013
Accepted: August 4, 2013
Published online: September 16, 2013
Core Tip
Core tip: This is a case of a 37-year-old gentleman presenting with chronic esophageal ulcers. Endoscopic biopsy samples were taken. Immunohistochemistry and hematoxylin and eosin staining of the biopsy samples were consistent with mucous associated lymphoid tissue (MALT) lymphoma. There was no sign of disease process in the stomach, and radiological studies revealed no evidence of metastasis. In consideration of these findings a diagnosis of primary esophageal MALT lymphoma was made, which is an extremely rare occurrence. On the basis of our experiences we recommend keeping primary esophageal MALT lymphoma in the differential diagnosis of chronic esophageal ulcers that are resistant to conservative management.