Systematic Reviews
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Aug 16, 2021; 13(8): 336-344
Published online Aug 16, 2021. doi: 10.4253/wjge.v13.i8.336
Effect of pancreatic endotherapy on quality of life in chronic pancreatitis patients: A systematic review
Samuel Y Han, Georgios I Papachristou, Raj J Shah, Darwin L Conwell
Samuel Y Han, Georgios I Papachristou, Darwin L Conwell, Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH 43210, United States
Raj J Shah, Division of Gastroenterology and Hepatology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, United States
Author contributions: Han SY and Conwell DL wrote the paper; Papachristou GI and Shah RJ reviewed and revised the paper.
Conflict-of-interest statement: Papachristou GI is a Consultant for Olympus, and has received research funding from AbbVie; Author Shah RJ is an Advisory Board Member and Consultant for Boston Scientific and Consultant for Olympus and Cook Endoscopy; Conwell DC received support from the National Cancer Institute and National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health under award number U01 DK108327.
PRISMA 2009 Checklist statement: This manuscript was presented in accordance with the PRISMA guidelines for a systematic review.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Samuel Y Han, MD, MS, Assistant Professor, Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Wexner Medical Center, 395 W 12th Ave. 2nd Floor Doan Office Tower, Columbus, OH 43210, United States. samuel.han@osumc.edu
Received: February 12, 2021
Peer-review started: February 12, 2021
First decision: May 5, 2021
Revised: June 11, 2021
Accepted: July 13, 2021
Article in press: July 13, 2021
Published online: August 16, 2021
Core Tip

Core Tip: Chronic pancreatitis remains difficult to treat and pancreatic endotherapy offers one option for the management of chronic pancreatitis-related complications. Pancreatic duct decompression via pancreatic duct stone lithotripsy and stenting appears to improve the quality of life of these patients in the short-term. More studies, however, are needed to examine the effect of endotherapy modalities such as endoscopic transmural drainage of pancreatic fluid collections, celiac plexus blocks and more recent innovations on quality of life in these patients.