Retrospective Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Oct 16, 2021; 13(10): 510-517
Published online Oct 16, 2021. doi: 10.4253/wjge.v13.i10.510
Safety of upper endoscopy in patients with active cocaine use
Anabel Liyen Cartelle, Alexander Nguyen, Parth M Desai, Vikram Kotwal, Jinal Makhija, Jie Yu, John Erikson L Yap
Anabel Liyen Cartelle, Department of Medicine, Beth Israel Deaconess Hospital, Boston, MA 02215, United States
Alexander Nguyen, Jie Yu, Division of Gastroenterology and Hepatology, John H. Stroger, Jr. Hospital of Cook County, Chicago, IL 60612, United States
Parth M Desai, Internal Medicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, IL 60612, United States
Vikram Kotwal, Division of Digestive Diseases, Rush University, Chicago, IL 60612, United States
Jinal Makhija, Division of Infectious Diseases, Rush University, Chicago, IL 60612, United States
John Erikson L Yap, Division of Gastroenterology and Hepatology, Augusta University, Augusta, GA 30912, United States
Author contributions: Liyen Cartelle A, Nguyen A and Desai PM wrote the report; Nguyen A, Desai PM, Kotwal V, Yu J, and Yap JEL designed, performed the research; Kotwal V, Yu J, and Yap JEL supervised the report; Desai PM and Makhija J contributed to the analysis.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of the John H. Stroger, Jr. Hospital of Cook County
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: We have no financial relationships to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Anabel Liyen Cartelle, MD, Doctor, Department of Medicine, Beth Israel Deaconess Hospital, 330 Brookline Ave, Boston, MA 02215, United States. anabelliyencartelle@gmail.com
Received: May 26, 2021
Peer-review started: May 26, 2021
First decision: June 12, 2021
Revised: July 1, 2021
Accepted: August 24, 2021
Article in press: August 24, 2021
Published online: October 16, 2021
Core Tip

Core Tip: There is no data available regarding safety of performing an esophagogastroduodenoscopy in patients with evidence of recent cocaine use. This study compared the prevalence of procedure complications between active and remote cocaine users and found no statistically significant difference between the two groups. Pre- and post-procedure hemodynamics demonstrated only statistically, but not clinically significant changes in blood pressure, heart rate, and oxygenation. Results suggest relative safety in performing this procedure on active cocaine users. Patients in the active group required more general anesthesia; however, given nature of study, the reasoning behind this sedation choice was difficult to determine.