Ihara E, Matsuzaka H, Honda K, Hata Y, Sumida Y, Akiho H, Misawa T, Toyoshima S, Chijiiwa Y, Nakamura K, Takayanagi R. Mucosal-incision assisted biopsy for suspected gastric gastrointestinal stromal tumors. World J Gastrointest Endosc 2013; 5(4): 191-196 [PMID: 23596545 DOI: 10.4253/wjge.v5.i4.191]
Corresponding Author of This Article
Eikichi Ihara, MD, PhD, Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. eikichi@intmed3.med.kyushu-u.ac.jp
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Eikichi Ihara, Kazuhiko Nakamura, Ryoichi Takayanagi, Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Higashi-ku, Fukuoka 812-8582, Japan
Hiroshi Matsuzaka, Yoshiharu Chijiiwa, Department of Gastroenterology, Hara-Sanshin General Hospital, Fukuoka 812-0033, Japan
Kuniomi Honda, Yoshitaka Hata, Yorinobu Sumida, Hirotada Akiho, Tadashi Misawa, Department of Gastroenterology, Kitakyushu Municipal Medical Center, Kokurakitaku, Kitakyushu 802-0077, Japan
Satoshi Toyoshima, Department of Pathology, Kitakyushu Municipal Medical Center, Kokurakitaku, Kitakyushu 802-0077, Japan
Author contributions: Ihara E, Matsuzaka H, Honda K, Hata Y, Sumida Y, Akiho H and Misawa T performed procedure of mucosal-incision assisted biopsy; Ihara E mainly wrote the manuscript; Toyoshima S contributed to pathological analysis of the biopsied samples; Misawa T, Chijiiwa Y, Nakamura K and Takayanagi R designed the study and edited the manuscript.
Correspondence to: Eikichi Ihara, MD, PhD, Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. eikichi@intmed3.med.kyushu-u.ac.jp
Telephone: +81-92-6425286 Fax: +81-92-6425287
Received: November 2, 2012 Revised: January 16, 2013 Accepted: January 23, 2013 Published online: April 16, 2013 Processing time: 164 Days and 21.4 Hours
Abstract
To evaluate the diagnostic yield of the procedure, mucosal-incision assisted biopsy (MIAB), for the histological diagnosis of gastric gastrointestinal stromal tumor (GIST), we performed a retrospective review of the 27 patients with suspected gastric GIST who underwent MIAB in our hospitals. Tissue samples obtained by MIAB were sufficient to make a histological diagnosis (diagnostic MIAB) in 23 out of the 27 patients, where the lesions had intraluminal growth patterns. Alternatively, the samples were insufficient (non-diagnostic MIAB) in remaining 4 patients, three of whom had gastric submucosal tumor with extraluminal growth patterns. Although endoscopic ultrasound and fine needle aspiration is the gold standard for obtaining tissue specimens for histological and cytological analysis of suspected gastric GISTs, MIAB can be used as an alternative method for obtaining biopsy specimens of lesions with an intraluminal growth pattern.
