Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Oct 28, 2015; 7(24): 2535-2542
Published online Oct 28, 2015. doi: 10.4254/wjh.v7.i24.2535
Roles of lipoprotein receptors in the entry of hepatitis C virus
Jingya Lyu, Hitomi Imachi, Kensaku Fukunaga, Takuo Yoshimoto, Huanxiang Zhang, Koji Murao
Jingya Lyu, Hitomi Imachi, Kensaku Fukunaga, Takuo Yoshimoto, Koji Murao, Department of Endocrinology and Metabolism, Faculty of Medicine, Kagawa University, Kagawa 761-0793, Japan
Jingya Lyu, Huanxiang Zhang, Department of Cell Biology, Medical College of Soochow University, Jiangsu Key Laboratory of Stem Cell Research, Suzhou 215123, Jiangsu Province, China
Author contributions: Lyu J contributed to summarize all the points and draft the article; Imachi H, Fukunaga K and Yoshimoto T contributed to collect and interpret the data; Zhang H and Murao K contributed to design of the study and final approval of the version of the article to be published.
Supported by The Ministry of Education, Culture, Sports, Science and Technology to Hitomi Imachi, Koji Murao, Japan, Nos. 24591352, 15K09415; and National Natural Science Foundation of China to Huanxiang Zhang, Nos. 31371407 and 31071220.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Koji Murao, MD, PhD, Professor, Department of Endocrinology and Metabolism, Faculty of Medicine, Kagawa University, 1750-1, Miki-cho, Kita-gun, Kagawa 761-0793, Japan.
Telephone: +81-878-912230
Received: June 27, 2015
Peer-review started: June 29, 2015
First decision: July 25, 2015
Revised: August 24, 2015
Accepted: September 25, 2015
Article in press: September 28, 2015
Published online: October 28, 2015
Core Tip

Core tip: As cirrhosis and hepatocellular carcinoma caused by hepatitis C virus (HCV) is one of the major health problems in the world, the investigation of HCV infection becomes more and more important. HCV entry is the initial step to start infection and is a multiple process involved in abnormal metabolism of lipid. Hence, here we summarize recent knowledge about the role of lipoprotein receptors for better understanding of HCV.