Ramírez-Mejía MM, Martínez-Sánchez FD, Córdova-Gallardo J, Méndez-Sánchez N. Evaluating the RESET care program: Advancing towards scalable and effective healthcare solutions for metabolic dysfunction-associated liver disease. World J Hepatol 2025; 17(4): 105254 [DOI: 10.4254/wjh.v17.i4.105254]
Corresponding Author of This Article
Nahum Méndez-Sánchez, MD, MSc, PhD, FAASLD, FACG, AGAF, Professor, Liver Research Unit, Medica Sur Clinic and Foundation, Puente de Piedra 150, Col. Toriello Guerra, Mexico City 14050, Mexico. nah@unam.mx
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Letter to the Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Hepatol. Apr 27, 2025; 17(4): 105254 Published online Apr 27, 2025. doi: 10.4254/wjh.v17.i4.105254
Evaluating the RESET care program: Advancing towards scalable and effective healthcare solutions for metabolic dysfunction-associated liver disease
Mariana M Ramírez-Mejía, Froylan D Martínez-Sánchez, Jacqueline Córdova-Gallardo, Nahum Méndez-Sánchez
Mariana M Ramírez-Mejía, Plan of Combined Studies in Medicine, Faculty of Medicine, National Autonomous University of Mexico, Mexico City 04360, Mexico
Mariana M Ramírez-Mejía, Nahum Méndez-Sánchez, Liver Research Unit, Medica Sur Clinic and Foundation, Mexico City 14050, Mexico
Froylan D Martínez-Sánchez, Department of Internal Medicine, Hospital General “Dr. Manuel Gea González”, Mexico City 4800, Mexico
Jacqueline Córdova-Gallardo, Department of Hepatology, Hospital General “Dr. Manuel Gea González”, Mexico City 4800, Mexico
Nahum Méndez-Sánchez, Faculty of Medicine, National Autonomous University of Mexico, Mexico City 04360, Mexico
Author contributions: Ramírez-Mejía MM and Martinez-Sanchez FD designed the overall concept and outline of the manuscript; Córdova-Gallardo J and Ramírez-Mejía MM contributed to the discussion and design of the manuscript; Martinez-Sanchez FD, Córdova-Gallardo J, Ramírez-Mejía MM, and Méndez-Sánchez N contributed to the writing and editing of the manuscript, illustrations, and review of the literature; and all authors thoroughly reviewed and endorsed the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Nahum Méndez-Sánchez, MD, MSc, PhD, FAASLD, FACG, AGAF, Professor, Liver Research Unit, Medica Sur Clinic and Foundation, Puente de Piedra 150, Col. Toriello Guerra, Mexico City 14050, Mexico. nah@unam.mx
Received: January 16, 2025 Revised: February 26, 2025 Accepted: March 8, 2025 Published online: April 27, 2025 Processing time: 99 Days and 14.2 Hours
Core Tip
Core Tip: This article discusses the effectiveness of the RESET care program, a digital health intervention integrating a personalized diet, structured exercise, and cognitive behavioral therapy for managing metabolic dysfunction-associated liver disease. Delivered via a mobile app supported by Internet of Things devices, the program provides real-time, patient-centred monitoring and support. The study demonstrated that participants receiving the full intervention (diet, exercise, and cognitive behavioral therapy) achieved superior weight reduction and anthropometric improvements, meeting the critical 7% weight loss threshold for improving metabolic dysfunction-associated liver disease outcomes. The RESET care program underscores the transformative potential of digital health platforms in providing scalable, effective solutions for chronic disease management.
