Observational Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Jan 27, 2025; 17(1): 101630
Published online Jan 27, 2025. doi: 10.4254/wjh.v17.i1.101630
Effectiveness of RESET care program: A real-world-evidence on managing non-alcoholic fatty liver disease through digital health interventions
Jayesh Soni, Nikhilesh Pathak, Mihir Gharia, Devina Aswal, Jaymin Parikh, Prachi Sharma, Astha Mishra, Dhvni Lalan, Twinkle Maheshwari
Jayesh Soni, Department of Gastroenterology, Digestive Disease Clinic, Mumbai 400092, Mahārāshtra, India
Nikhilesh Pathak, Department of Endocrinology, DPC Health and Diabetic Clinic, Delhi 110008, India
Mihir Gharia, Devina Aswal, Jaymin Parikh, Prachi Sharma, Astha Mishra, Dhvni Lalan, Twinkle Maheshwari, Medical Affairs, Tatvacare, Ahmedabad 380058, Gujarāt, India
Author contributions: Soni J and Pathak N conducted patient enrollment and data collection; Parikh J and Sharma P wrote, and edited the manuscript; Aswal D and Gharia M supervised the study; Mishra A created the images and graphics; Lalan D and Maheshwari T assisted with data analysis and manuscript revisions.
Institutional review board statement: The study received approval from the ACEAS-Independent Ethics Committee with protocol number: MTNAFLD120324.
Informed consent statement: Upon onboarding to MyTatva app, all participants were informed about the use of the digital health app and associated monitoring tools. They provided consent to participate and agreed to the collection and use of their data for research purposes.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Data sharing statement: No additional data are available for this study. The dataset analyzed was fully anonymized, and no further information can be provided beyond the results presented in this manuscript.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mihir Gharia, Medical Affairs, Tatvacare, Plot No. 115/5, No. 51 TP Scheme Road, Ahmedabad 380058, Gujarāt, India. mihir10584@gmail.com
Received: September 23, 2024
Revised: November 11, 2024
Accepted: December 2, 2024
Published online: January 27, 2025
Processing time: 106 Days and 19.9 Hours
Core Tip

Core Tip: This study evaluates the RESET care program, a comprehensive digital health intervention for managing non-alcoholic fatty liver disease (NAFLD). By integrating personalized diet, exercise, and cognitive behavioral therapy (CBT) through a mobile app supported by internet of things devices, the program offers continuous, tailored support for lifestyle modifications crucial to NAFLD management. Results demonstrate that participants receiving all three interventions (diet, exercise, CBT) achieved significant weight reduction and improved health outcomes. The RESET care program highlights the potential of digital tools in delivering accessible, scalable solutions for chronic disease management.