Case Report
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World J Hepatol. Feb 27, 2022; 14(2): 471-478
Published online Feb 27, 2022. doi: 10.4254/wjh.v14.i2.471
Glycogen hepatopathy in type-1 diabetes mellitus: A case report
Yuvaraj Singh, Susant Gurung, Maya Gogtay
Yuvaraj Singh, Susant Gurung, Maya Gogtay, Internal Medicine, Saint Vincent Hospital, Worcester, MA 01604, United States
Author contributions: Singh Y wrote down the manuscript, collected data, directly involved in patient care; Gogtay M collected imaging of the patient, assisted in procuring biopsy specimen of the patient; Gurung S contributed to collecting patients past medical history and literature review on the diagnosis; all authors have read and approved the final manuscript.
Informed consent statement: We obtained informed written consent from the patients to anonymously report the findings pertaining to her case.
Conflict-of-interest statement: We would like to report no conflict of interest for this case report. We have no disclosures.
CARE Checklist (2016) statement: Manuscript meets the requirements of the CARE Checklist - 2016: Information for writing a case report.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yuvaraj Singh, MD, Doctor, Internal Medicine, Saint Vincent Hospital, 123 Summer Street, Worcester, MA 01604, United States. yuvaraj.singh@stvincenthospital.com
Received: October 12, 2021
Peer-review started: October 12, 2021
First decision: November 17, 2021
Revised: November 19, 2021
Accepted: January 11, 2022
Article in press: January 11, 2022
Published online: February 27, 2022
Processing time: 132 Days and 17.4 Hours
Core Tip

Core Tip: Glycogen hepatopathy is a poorly understood complication of type 1 diabetes mellitus patients who have poor glycemic control. Its presentation can closely mimic non-alcoholic fatty liver disease creating a diagnostic enigma in patients with diabetes. After excluding other common causes of hepatitis, one must keep this elusive diagnosis in mind. Hepatic biopsy has been the mainstay for diagnosis, however, with recent advancements sequential magnetic resonance imaging and computed tomography scans are also sensitive but limited by availability.