Gaspar R, Castelo Branco C, Macedo G. Liver and COVID-19: From care of patients with liver diseases to liver injury. World J Hepatol 2021; 13(10): 1367-1377 [PMID: 34786172 DOI: 10.4254/wjh.v13.i10.1367]
Corresponding Author of This Article
Rui Gaspar, MD, Doctor, Department of Gastroenterology and Hepatology, Centro Hospitalar de São João, Alameda Prof Hernani Monteiro, Porto 4200, Portugal. ruilopesgaspar@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Rui Gaspar, Guilherme Macedo, Department of Gastroenterology and Hepatology, Centro Hospitalar de São João, Porto 4200, Portugal
Catarina Castelo Branco, Department of Internal Medicine, Centro Hospitalar e Universitário do Porto, Porto 4100, Portugal
Author contributions: Gaspar R and Branco CC were responsible for acquisition and interpretation of data and drafting of the manuscript; and Macedo G was responsible for critical revision of the manuscript.
Conflict-of-interest statement: The authors declare no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Rui Gaspar, MD, Doctor, Department of Gastroenterology and Hepatology, Centro Hospitalar de São João, Alameda Prof Hernani Monteiro, Porto 4200, Portugal. ruilopesgaspar@gmail.com
Received: May 28, 2021 Peer-review started: May 28, 2021 First decision: June 27, 2021 Revised: July 11, 2021 Accepted: August 31, 2021 Article in press: August 31, 2021 Published online: October 27, 2021 Processing time: 146 Days and 18.2 Hours
Core Tip
Core Tip: Coronavirus disease 2019 (COVID-19) has become a major health problem worldwide in the last few months, affecting the health system dramatically. Apart from the respiratory system, associated liver injury is one of the main concerns in severe acute respiratory syndrome coronavirus 2 infection and several mechanisms could explain liver abnormalities. In this mini-review, and different from other papers, we not only analyze liver injury by COVID-19, the effect of COVID-19 in liver diseases, its pathophysiology and strategies to keep an adequate care of liver patients, but also highlight the potential higher risk of severe disease or risk of infection in patients with different etiologies of liver disease. We also analyze the recent recommendations and prioritization regarding vaccination in patients with liver disease.
