Published online May 27, 2020. doi: 10.4254/wjh.v12.i5.230
Peer-review started: December 6, 2019
First decision: December 26, 2019
Revised: February 29, 2020
Accepted: April 4, 2020
Article in press: April 4, 2020
Published online: May 27, 2020
Alcoholic liver disease (ALD) is one of the main causes of chronic liver disease worldwide. Individuals with long-term significant alcohol consumption remain at risk for liver disease that may range from alcoholic steatohepatitis to cirrhosis and hepatocellular carcinoma.
It is important to know the epidemiology of ALD within a specific region/country to better understand which resources might be necessary to improve management. ALD might have been overlooked in recent years due to recent therapy advances in other Hepatology fields.
To describe the epidemiological profile of hospital admissions due to ALD in different regions of Brazil from 2006 to 2015, including the mortality rates and admissions according to age range.
This is a descriptive study that has evaluated aggregate data. Data from the five Brazilian geographic regions were used for the study.
There was a 34.07% increase in the total number of admissions over these 10 years, from 12879 in 2006 to 17267 in 2015 as well as a 24.72% increase in the total number of ALD deaths between 2006 and 2015. We found that the age group between 50 and 59 years had the highest proportion of both hospitalizations and deaths: 28.94% (n = 46329) of total hospital admissions and 29.43% (n = 28864) of all deaths. Men were more frequently hospitalized than women and had the highest proportions of deaths in all regions. Mortality coefficient rates increased over the years, and simple linear regression analysis indicated a statistically significant upward trend in this mortality (R² = 0.744).
Our study has provided a landscape of the epidemiological profile of public hospital admissions due to ALD in Brazil. We detected an increase in the total number of admissions and deaths due to ALD over 10 years.
This study signals the need to be alert to this liver illness and to possibly revisit policies related to alcohol marketing, sales, and consumption.