Systematic Reviews
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Sep 8, 2016; 8(25): 1087-1092
Published online Sep 8, 2016. doi: 10.4254/wjh.v8.i25.1087
Hydatid cyst of the gallbaldder: A systematic review of the literature
Roberto Gómez, Yousef Allaoua, Rafael Colmenares, Sergio Gil, Pilar Roquero, José M Ramia
Roberto Gómez, Yousef Allaoua, Rafael Colmenares, Sergio Gil, Pilar Roquero, Faculty of Medicine, Universidad de Alcalá, 28805 Alcalá de Henares, Spain
José M Ramia, Servicio de Cirugía General y del Aparato Digestivo, Hospital Universitario de Guadalajara, 19002 Guadalajara, Spain
Author contributions: Gómez R, Allaoua Y, Comenares R, Gil S and Roquero P analyzed data; Gómez R, Allaoua Y, Comenares R, Gil S, Roquero P and Ramia JM wrote the manuscript; Ramia JM performed research.
Conflict-of-interest statement: Authors declare no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: José M Ramia, MD, PhD, FACS, FRCS, Servicio de Cirugía General y del Aparato Digestivo, Hospital Universitario de Guadalajara, C/Donantes de Sangre s/n. 7ª planta, 19002 Guadalajara, Spain.
Telephone: +34-61-6292056 Fax: +34-94-9209218
Received: April 11, 2016
Peer-review started: April 13, 2016
First decision: May 17, 2016
Revised: July 4, 2016
Accepted: July 29, 2016
Article in press: August 1, 2016
Published online: September 8, 2016

To evaluate all the references about primary gallbladder hidatidosis looking for best treatment evidence.


Search: 1966-2015 in MEDLINE, Cochrane Library, SciELO, and Tripdatabase. Key words: “gallabladder hydatid disease” and “gallbladder hydatid cyst”. We found 124 papers in our searches but only 14 papers including 16 cases were about hydatid cyst of the gallbladder (GBHC).


Eight cases of GBHC were women and seven men. One not mentioned. Median age was 48.3 years. The most frequent clinical symptom was abdominal pain (94%) usually in the right upper quadrant. Ultrasound was performed in ten patients (62.5%) but in most cases a combination of several techniques was performed. The location of the cysts was intravesicular in five patients. Five patients presented GBHC and liver hydatid cysts. Two patients presented cholelithiasis and one choledocholithiasis. The most frequent surgical technique was cholecystectomy by laparotomy (81.25%). Simultaneous surgery of liver cysts was carried out in five cases. Eleven patients did not present postoperative complications, but one died. The mean hospital stay was seven days. No recurrence of GBHC was recorded.


In GBHC, the most frequent symptom is right hypocondrium pain (evidence level V). Best diagnostic methods are ultrasound and computed tomography (level V, grade D). Suggested treatment is open cholecystectomy and postoperative albendazole (level V, grade D) obtaining good clinical results and none relapses.

Keywords: Hydatid cyst, Gallbladder, Cholecystectomy, Review, Hydatidosis

Core tip: Systematic review of gallbladder hydatidosis has not previously done. We have performed a systematic search trying to define best diagnostic procedures and best therapeutical strategies.