Basic Study
Copyright ©The Author(s) 2024.
World J Stem Cells. Feb 26, 2024; 16(2): 191-206
Published online Feb 26, 2024. doi: 10.4252/wjsc.v16.i2.191
Table 1 The Pelletier gross scoring criteria
Articular surface conditions
Rating
The articular surfaces are intact and of normal color0
The articular surface is slightly rough, with small fissures visible and loss of luster1
Mild damage to the articular surface, with cartilage damage reaching the superficial or middle cartilage layer2
The articular surface is heavily damaged, with the defect reaching deep into the cartilage but not yet exposing the subchondral bone3
The cartilage defect is severe, and the subchondral bone is exposed or even damaged4
Table 2 The Lequesne MG rating criteria

Level 1
Level 2
Level 3
Level 4
Pain conditionsNo significant reactionAvoidance contraction of the affected limb following compressionAvoided contraction of the affected limb and turn back, body out present tremorViolent contraction of the affected limb, violent shaking and struggling of the body
GaitNormal gaitMild limp but strong stirring of the affected limbThe limp is pronounced, and the strength of the affected limb to stir on the ground is reducedThe affected limb is afraid to walk on the ground
Knee range of motion> 90°45°-90°15°-45°< 15°
SwellingNo swelling and clear bony markingsMild swelling with superficial bony markingsSignificant swelling and loss of bony markings
Table 3 Comparison of Lequesne MG grades at three different time points
GroupLocalized pain assessment
Gait assessment
Knee joint range of motion assessment
Swelling condition assessment
Level 1
Level 2
Level 3
Level 4
Level 1
Level 2
Level 3
Level 4
Level 1
Level 2
Level 3
Level 4
Level 1
Level 2
Level 3
4-wk NC group264017400831084
4-wk Exo group831038106510930
4-wk E-Exo group11100462075001020
8-wk NC group013202310132024
8-wk Exo group321023100420330
8-wk E-Exo group420014102310420