Molecular mechanisms of mesenchymal stem cell differentiation towards osteoblasts

doi:10.4252/wjsc.v5.i4.136

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Oct 26, 2013; 5(4): 136-148
Published online Oct 26, 2013. doi: 10.4252/wjsc.v5.i4.136

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Figure 1 transcription factors involved in osteoblast differentiation form mesenchymal stem cells. Markers of differentiation are shown in black, stimulatory transcription factors in green, and inhibitory ones in red. MSCs: Mesenchymal stem cells; ATF4: Activating transcription factor 4; C/EBP: CCAAT/enhancer-binding proteins; Coll: Collagen; DMP-1: Dentin matrix protein-1; Ob: Osteoblast; Osx: Osterix; PPAR: Peroxysome proliferator activated receptor; SATB2: Special AT-rich sequence binding protein 2; TAZ: Transcription coactivator with binding capacity to PDZ motifs; TNAP: Tissue-nonspecific alkaline phosphatase; Runx2: Runt-related 2.

Citation: Fakhry M, Hamade E, Badran B, Buchet R, Magne D. Molecular mechanisms of mesenchymal stem cell differentiation towards osteoblasts. World J Stem Cells 2013; 5(4): 136-148
URL: https://www.wjgnet.com/1948-0210/full/v5/i4/136.htm
DOI: https://dx.doi.org/10.4252/wjsc.v5.i4.136