Copyright ©The Author(s) 2022.
World J Stem Cells. Jan 26, 2022; 14(1): 92-103
Published online Jan 26, 2022. doi: 10.4252/wjsc.v14.i1.92
Figure 1
Figure 1 A brief illustration of the interactions between long noncoding RNAs and the epigenetic modification associated with osteo-/adipogenic differentiation of mesenchymal stromal cells and osteoarthritis. Histone acetylation and H3K4me3 are believed to promote transcription, whereas DNA methylation, H3K9me3 and H3K27me3 restrict gene expression. OD: Osteogenic differentiation; AD: Adipogenic differentiation; OA: Osteoarthritis.