Epigenetic regulation by long noncoding RNAs in osteo-/adipogenic differentiation of mesenchymal stromal cells and degenerative bone diseases

doi:10.4252/wjsc.v14.i1.92

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Jan 26, 2022 (publication date) through Apr 24, 2024

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Jan 26, 2022; 14(1): 92-103
Published online Jan 26, 2022. doi: 10.4252/wjsc.v14.i1.92

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Figure 1 A brief illustration of the interactions between long noncoding RNAs and the epigenetic modification associated with osteo-/adipogenic differentiation of mesenchymal stromal cells and osteoarthritis. Histone acetylation and H3K4me3 are believed to promote transcription, whereas DNA methylation, H3K9me3 and H3K27me3 restrict gene expression. OD: Osteogenic differentiation; AD: Adipogenic differentiation; OA: Osteoarthritis.

Citation: Xia K, Yu LY, Huang XQ, Zhao ZH, Liu J. Epigenetic regulation by long noncoding RNAs in osteo-/adipogenic differentiation of mesenchymal stromal cells and degenerative bone diseases. World J Stem Cells 2022; 14(1): 92-103
URL: https://www.wjgnet.com/1948-0210/full/v14/i1/92.htm
DOI: https://dx.doi.org/10.4252/wjsc.v14.i1.92