Editorial
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Stem Cells. Mar 26, 2015; 7(2): 235-242
Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.235
SIRT1 and stem cells: In the forefront with cardiovascular disease, neurodegeneration and cancer
Kenneth Maiese
Kenneth Maiese, Cellular and Molecular Signaling, Newark, NJ 07101, United States
Author contributions: Maiese K conceived, designed, and wrote this article.
Supported by The following grants to Kenneth Maiese: American Diabetes Association; American Heart Association; NIH NIEHS; NIH NIA; NIH NINDS; and NIH ARRA.
Conflict-of-interest: The author declares no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Kenneth Maiese, MD, Cellular and Molecular Signaling, 125 Main Street, Newark, NJ 07101, United States. wntin75@yahoo.com
Received: November 2, 2014
Peer-review started: November 2, 2014
First decision: November 27, 2014
Revised: December 31, 2014
Accepted: January 15, 2015
Article in press: January 15, 2015
Published online: March 26, 2015
Processing time: 138 Days and 9.4 Hours
Core Tip

Core tip: SIRT1, a mammalian homologue of the yeast silent information regulator-2, holds exciting prospects for new therapeutic strategies that can offer reparative processes for cardiac, vascular, and nervous system degenerative disorders as well as targeted control of unchecked cell growth during cancer.