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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Stem Cells. Jul 26, 2014; 6(3): 288-295
Published online Jul 26, 2014. doi: 10.4252/wjsc.v6.i3.288
Published online Jul 26, 2014. doi: 10.4252/wjsc.v6.i3.288
Osteogenic potential: Comparison between bone marrow and adipose-derived mesenchymal stem cells
Han-Tsung Liao, Department of Plastic and Reconstructive Surgery, Craniofacial Research Center, Chang Gung Memorial Hospital at Linko, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan
Chien-Tzung Chen, Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital at Keelung, College of Medicine, Chang Gung University, Keelung 222, Taiwan
Author contributions: Liao HT reviewed the literature and wrote the paper; Chen CT revised the paper critically and approved the final version for publication.
Supported by Chang Gung Memorial Hospital, No. CMRPG381331-3, No. CMPRG381321-3 and No. CMRPG381311-3
Correspondence to: Chien-Tzung Chen, MD, Professor, Department of Plastic and Reconstruction Surgery, Chang Gung Memorial Hospital at Keelung, College of Medicine, Chang Gung University, Maijin Road, Keelung 222, Taiwan. ctchenap@cgmh.org.tw
Telephone: +886-2-24313131 Fax: +886-2-24313161
Received: October 26, 2013
Revised: January 17, 2014
Accepted: April 25, 2014
Published online: July 26, 2014
Processing time: 266 Days and 8.1 Hours
Revised: January 17, 2014
Accepted: April 25, 2014
Published online: July 26, 2014
Processing time: 266 Days and 8.1 Hours
Core Tip
Core tip: Both bone marrow stem cells (BMSC) and adipose-derived stem cells (ASC) have been reported to have the osteogenic capacity in vitro and in vivo. ASCs possess some attractive characters for clinical application compared to BMSCs, such as abundant stem cells from lipoaspirates, faster growth and less discomfort and morbidity during surgery. Nevertheless, the arising question is that “Is the osteogenic capacity of ASCs the same or far better than BMSCs?”. The purpose of this review paper is to compare the osteogenic capacity between BMSCs and ASCs based on the literatures which using both BMSCs and ASCs simultaneously in their articles.