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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Stem Cells. Jul 26, 2014; 6(3): 256-265
Published online Jul 26, 2014. doi: 10.4252/wjsc.v6.i3.256
Published online Jul 26, 2014. doi: 10.4252/wjsc.v6.i3.256
Adipose-derived mesenchymal stromal/stem cells: An update on their phenotype in vivo and in vitro
Patrick C Baer, Division of Nephrology, Department of Internal Medicine III, Goethe-University, 60590 Frankfurt/M, Germany
Author contributions: Baer PC solely contributed to this paper.
Correspondence to: Patrick C Baer, MD, PhD, Division of Nephrology, Department of Internal Medicine III, Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt/M, Germany. p.baer@em.uni-frankfurt.de
Telephone: +49-69-63015554 Fax: +49-69-63014749
Received: December 26, 2013
Revised: May 31, 2014
Accepted: June 14, 2014
Published online: July 26, 2014
Processing time: 204 Days and 23.2 Hours
Revised: May 31, 2014
Accepted: June 14, 2014
Published online: July 26, 2014
Processing time: 204 Days and 23.2 Hours
Core Tip
Core tip: Adipose tissue is a rich, ubiquitously available and easily accessible source for multipotent stromal/stem cells. This review gives an update of the recently published data on the origin and phenotype of adipose-derived stromal/stem cells (ASCs) both in vivo and in vitro. Furthermore, since many aspects of ASCs, such as the differential potential or the current use in clinical trials, are fully described in other recent reviews, this review also updates the more basic research issues concerning ASCs’ subpopulations, heterogeneity and culture standardization.