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World J Stem Cells. Apr 26, 2014; 6(2): 173-178
Published online Apr 26, 2014. doi: 10.4252/wjsc.v6.i2.173
Mesenchymal stem cells in treating autism: Novel insights
Dario Siniscalco, James Jeffrey Bradstreet, Nataliia Sych, Nicola Antonucci
Dario Siniscalco, Department of Experimental Medicine, Second University of Naples, 16-80138 Napoli, Italy
Dario Siniscalco, Centre for Autism, La Forza del Silenzio, 81036 Caserta, Italy
Dario Siniscalco, Cancellautismo, 50132 Florence, Italy
James Jeffrey Bradstreet, Brain Treatment Center, Buford, GA 30518, United States
Nataliia Sych, Clinical Department, Cell Therapy Center EmCell, 04073 Kiev, Ukraine
Nicola Antonucci, Biomedical Centre for Autism Research and Treatment, 70126 Bari, Italy
Author contributions: Siniscalco D designed the paper; Siniscalco D and Bradstreet JJ wrote the paper; Sych N contributed to the paragraph on MSCs; Antonucci N contributed to the paragraph on autism; Bradstreet JJ edited the English language.
Correspondence to: Dario Siniscalco, ChemD, PhD, Department of Experimental Medicine, Second University of Naples, Via S Maria di Costantinopoli, 16-80138 Napoli, Italy. dariosin@uab.edu
Telephone: +39-81-5665880 Fax: +39-81-5667503
Received: November 11, 2013
Revised: December 19, 2013
Accepted: March 17, 2014
Published online: April 26, 2014
Core Tip

Core tip: Autism spectrum disorders are still untreatable pathologies. Mesenchymal stem cells possess the immunological properties which make them promising candidates as a novel therapeutic option.